Kossard S, Winkelmann R K
Am J Dermatopathol. 1979 Spring;1(1):27-34.
Calcification in cutaneous blood vessels is an uncommon finding in biopsies submitted for dermatopathological examination. Of 14 biopsy specimens showing the phenomenon that was studied by us, the greater number was from women who had a combination of severe diabetes, hypertension, and atherosclerosis. Unusual clinical syndromes as the bases for the vascular calcification were hyperthyroidism in three patients and arteritis in two patients. Three patients died as a consequence of massive cutaneous infarction and sepsis, probably stemming from cutaneous vascular calcification. Vascular calcification in biopsy of skin may result from metabolic, inflammatory, or degenerative diseases of blood vessels.
皮肤血管钙化在提交进行皮肤病理检查的活检中是一种不常见的发现。在我们研究的14例显示该现象的活检标本中，大多数来自患有严重糖尿病、高血压和动脉粥样硬化的女性。作为血管钙化基础的不寻常临床综合征包括3例患者的甲状腺功能亢进和2例患者的动脉炎。3例患者死于大面积皮肤梗死和败血症，可能源于皮肤血管钙化。皮肤活检中的血管钙化可能由血管的代谢、炎症或退行性疾病引起。
