Leslie R G, Cohen S
Biochem J. 1970 Dec;120(4):787-95. doi: 10.1042/bj1200787.
The isolation of guinea-pig immunoglobulins gamma(1)G, gamma(2)G and gammaM are described and methods for separating the polypeptide chains of each examined. The molecular weights, extinction coefficients and carbohydrate and amino acid compositions of the immunoglobulins and their constituent chains have been analysed. The findings provide a basis for further studies attempting to relate structural differences to distinct biological properties of guinea-pig immunoglobulins.
本文描述了豚鼠免疫球蛋白γ(1)G、γ(2)G和γM的分离,并对每种免疫球蛋白的多肽链分离方法进行了研究。分析了免疫球蛋白及其组成链的分子量、消光系数、碳水化合物和氨基酸组成。这些发现为进一步研究豚鼠免疫球蛋白结构差异与不同生物学特性之间的关系提供了基础。