• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

从豚鼠颌下腺分离出的含激肽释放酶颗粒的特性

Properties of kallikrein-containing granules isolated from the submaxillary gland of the guinea-pig.

作者信息

Bhoola K D, Heap P F

出版信息

J Physiol. 1970 Sep;210(2):421-32. doi: 10.1113/jphysiol.1970.sp009218.

DOI:10.1113/jphysiol.1970.sp009218
PMID:5501268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1395569/
Abstract
  1. Granular fractions of high purity consisting of subcellular kallikrein- and amylase-storing organelles have been isolated from homogenates of guinea-pig submaxillary gland.2. The isolated kallikrein- and amylase-containing granules closely resembled secretory granules observed in situ in serous acinar cells in intra-granular appearance, size and histochemical reaction.3. The subcellular, histochemical and ultrastructural studies indicate that the serine protease, kallikrein, is like amylase an exocrine enzyme with a functional role in saliva.
摘要

  1. 已从豚鼠下颌下腺匀浆中分离出由储存亚细胞激肽释放酶和淀粉酶的细胞器组成的高纯度颗粒组分。

  2. 分离出的含激肽释放酶和淀粉酶的颗粒在颗粒外观、大小和组织化学反应方面与在浆液性腺泡细胞原位观察到的分泌颗粒非常相似。

  3. 亚细胞、组织化学和超微结构研究表明，丝氨酸蛋白酶激肽释放酶与淀粉酶一样，是一种在唾液中具有功能作用的外分泌酶。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/a217ff6ba90d/jphysiol01044-0187-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/7edc1e66e2d9/jphysiol01044-0185-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/7fe5d20b2f63/jphysiol01044-0185-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/76a8886baafd/jphysiol01044-0186-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/0d2c29e934b8/jphysiol01044-0186-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/a217ff6ba90d/jphysiol01044-0187-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/7edc1e66e2d9/jphysiol01044-0185-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/7fe5d20b2f63/jphysiol01044-0185-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/76a8886baafd/jphysiol01044-0186-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/0d2c29e934b8/jphysiol01044-0186-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b7b/1395569/a217ff6ba90d/jphysiol01044-0187-a.jpg

相似文献

1
Properties of kallikrein-containing granules isolated from the submaxillary gland of the guinea-pig.从豚鼠颌下腺分离出的含激肽释放酶颗粒的特性
J Physiol. 1970 Sep;210(2):421-32. doi: 10.1113/jphysiol.1970.sp009218.
2
The intracellular localization of kallikrein, trypsin and amylase in dog pancreas.激肽释放酶、胰蛋白酶和淀粉酶在犬胰腺中的细胞内定位。
J Physiol. 1971 May;214(3):553-70. doi: 10.1113/jphysiol.1971.sp009448.
3
Intracellular distribution of submaxillary kallikrein.颌下腺激肽释放酶的细胞内分布
J Physiol. 1968 May;196(2):431-45. doi: 10.1113/jphysiol.1968.sp008516.
4
Histochemical localization of kallikrein granules in the submaxillary gland of the guinea-pig.豚鼠颌下腺中激肽释放酶颗粒的组织化学定位。
J Anat. 1969 Nov;105(Pt 3):525-32.
5
The subcellular localization of kallikrein, amylase and acetylcholine in the submaxillary gland of the guinea-pig.豚鼠颌下腺中激肽释放酶、淀粉酶和乙酰胆碱的亚细胞定位。
J Physiol. 1966 Jun;184(3):663-72. doi: 10.1113/jphysiol.1966.sp007939.
6
The influence of androgens on enzymes (chymotrypsin-and trypsin-like proteases, renin, kallikrein and amylase) and on cellular structure of the mouse submaxillary gland.雄激素对小鼠颌下腺中酶（糜蛋白酶样和胰蛋白酶样蛋白酶、肾素、激肽释放酶及淀粉酶）及细胞结构的影响。
J Physiol. 1973 Dec;235(2):503-22. doi: 10.1113/jphysiol.1973.sp010400.
7
Secretory granules of murine salivary glands. A morphological, biochemical and morphological, biochemical and immunochemical study of submandibular and parotid granules.小鼠唾液腺的分泌颗粒。下颌下腺和腮腺颗粒的形态学、生物化学及免疫化学研究。
J Biol Buccale. 1982 Mar;10(1):11-30.
8
Ultrastructural immunolocalization of kallikrein in apical granules of striated duct cells of cat submandibular gland.猫下颌下腺纹状管细胞顶端颗粒中激肽释放酶的超微结构免疫定位
J Histochem Cytochem. 1983 Feb;31(2):345-7. doi: 10.1177/31.2.6339608.
9
Properties of plasma membrane-induced amylase release from rat parotid secretory granules: effects of Ca2+ and Mg-ATP.大鼠腮腺分泌颗粒中质膜诱导淀粉酶释放的特性：Ca2+和Mg-ATP的作用
Biochim Biophys Acta. 1992 Apr 22;1116(2):104-11. doi: 10.1016/0304-4165(92)90106-5.
10
Kallikrein in granules of the submaxillary gland.下颌下腺颗粒中的激肽释放酶。
Biochem Pharmacol. 1968 May;17(5):667-74. doi: 10.1016/0006-2952(68)90003-8.

引用本文的文献

1
The localization of kallikrein in the dog and guinea-pig submandibular glands.激肽释放酶在犬和豚鼠颌下腺中的定位。
Experientia. 1981;37(8):872-8. doi: 10.1007/BF01985689.
2
The intracellular localization of kallikrein, trypsin and amylase in dog pancreas.激肽释放酶、胰蛋白酶和淀粉酶在犬胰腺中的细胞内定位。
J Physiol. 1971 May;214(3):553-70. doi: 10.1113/jphysiol.1971.sp009448.
3
Kallikrein, trypsin-like proteases and amylase in mammalian submaxillary glands.哺乳动物颌下腺中的激肽释放酶、类胰蛋白酶和淀粉酶。

本文引用的文献

1
Some observations on salivary secretion.关于唾液分泌的一些观察
J Physiol. 1935 Aug 22;85(1):15-36. doi: 10.1113/jphysiol.1935.sp003299.
2
An assay procedure for a succinate-neotetrazolium-reductase system.琥珀酸 - 新四氮唑还原酶系统的测定方法。
Biochem J. 1960 Mar;74(3):591-6. doi: 10.1042/bj0740591.
3
Embedding in epoxy resins for ultrathin sectioning in electron microscopy.嵌入环氧树脂用于电子显微镜超薄切片。
Br J Pharmacol. 1971 Dec;43(4):784-93. doi: 10.1111/j.1476-5381.1971.tb07214.x.
4
The influence of androgens on enzymes (chymotrypsin-and trypsin-like proteases, renin, kallikrein and amylase) and on cellular structure of the mouse submaxillary gland.雄激素对小鼠颌下腺中酶（糜蛋白酶样和胰蛋白酶样蛋白酶、肾素、激肽释放酶及淀粉酶）及细胞结构的影响。
J Physiol. 1973 Dec;235(2):503-22. doi: 10.1113/jphysiol.1973.sp010400.
5
I. Ultrastructure of acinar cell granules in mammalian submaxillary glands.一、哺乳动物下颌下腺腺泡细胞颗粒的超微结构
Z Zellforsch Mikrosk Anat. 1972;126(3):320-34. doi: 10.1007/BF00306847.
6
Acinar ultrastructure of the submandibular gland of Mus musculus during embryonic development.小家鼠胚胎发育期间下颌下腺的腺泡超微结构
Cell Tissue Res. 1974;150(4):425-42. doi: 10.1007/BF00225967.
7
II. Ultrastructure of duct cell granules in mammalian submaxillary glands.二、哺乳动物下颌下腺导管细胞颗粒的超微结构
Z Zellforsch Mikrosk Anat. 1972;126(3):335-47. doi: 10.1007/BF00306848.
8
Autonomic nerve stimulation, kallikrein content anc acinar cell granules of the cat's submandibular gland.猫下颌下腺的自主神经刺激、激肽释放酶含量及腺泡细胞颗粒
J Physiol. 1975 Oct;251(2):363-9. doi: 10.1113/jphysiol.1975.sp011097.
9
Effect of nerve stimulation, denervation, and duct ligation, on kallikrein content and duct cell granules of the cat's submandibular gland.神经刺激、去神经支配和导管结扎对猫下颌下腺激肽释放酶含量及导管细胞颗粒的影响。
Experientia. 1977 Jun 15;33(6):746-8. doi: 10.1007/BF01944167.
10
Demilune cells of the cat submandibular gland; an unlikely source of kallikrein.猫下颌下腺的半月细胞；激肽释放酶的一个不太可能的来源。
Experientia. 1978 May 15;34(5):609-10. doi: 10.1007/BF01936988.
Stain Technol. 1960 Nov;35:313-23. doi: 10.3109/10520296009114754.
4
Purification and characteristics of an alkaline protease from rat-submandibular gland.大鼠下颌下腺碱性蛋白酶的纯化及特性
Biochim Biophys Acta. 1966 Jun 15;118(3):604-20. doi: 10.1016/s0926-6593(66)80101-7.
5
The subcellular localization of kallikrein, amylase and acetylcholine in the submaxillary gland of the guinea-pig.豚鼠颌下腺中激肽释放酶、淀粉酶和乙酰胆碱的亚细胞定位。
J Physiol. 1966 Jun;184(3):663-72. doi: 10.1113/jphysiol.1966.sp007939.
6
Isolation and purification of acid phosphatase-containing autofluorescent granules from homogenates of rat kidney cortex.从大鼠肾皮质匀浆中分离和纯化含酸性磷酸酶的自发荧光颗粒。
J Ultrastruct Res. 1966 Sep;16(1):13-34. doi: 10.1016/s0022-5320(66)80020-5.
7
Increases vascular permeability caused by the trypsin-like enzymes purified from rat submandibular gland.从大鼠下颌下腺纯化的类胰蛋白酶可增加血管通透性。
Acta Physiol Scand. 1969 Jan-Feb;75(1):157-60. doi: 10.1111/j.1748-1716.1969.tb04367.x.
8
Electron microscopy and histochemistry of isolated kallikrein granules.分离的激肽释放酶颗粒的电子显微镜检查与组织化学
Br J Pharmacol. 1970 Feb;38(2):435P-436P.
9
Kallikreins and kinins.激肽释放酶与激肽
Physiol Rev. 1969 Jul;49(3):509-47. doi: 10.1152/physrev.1969.49.3.509.
10
Histochemical localization of kallikrein granules in the submaxillary gland of the guinea-pig.豚鼠颌下腺中激肽释放酶颗粒的组织化学定位。
J Anat. 1969 Nov;105(Pt 3):525-32.