大鼠肝脏微粒体酶将菲9,10 - 氧化物和二苯并[a,h]蒽5,6 - 氧化物转化为二氢二醇。 - Suppr

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超能文献

The conversion of phenanthrene 9,10-oxide and dibenz[a,h]anthracene 5,6-oxide into dihydrodiols by a rat-liver microsomal enzyme.

作者信息

Pandov H, Sims P

出版信息

Biochem Pharmacol. 1970 Jan;19(1):299-303. doi: 10.1016/0006-2952(70)90349-7.

DOI:10.1016/0006-2952(70)90349-7

PMID:5507644

Abstract

摘要

相似文献

The conversion of phenanthrene 9,10-oxide and dibenz[a,h]anthracene 5,6-oxide into dihydrodiols by a rat-liver microsomal enzyme.大鼠肝脏微粒体酶将菲9,10 - 氧化物和二苯并[a,h]蒽5,6 - 氧化物转化为二氢二醇。

Biochem Pharmacol. 1970 Jan;19(1):299-303. doi: 10.1016/0006-2952(70)90349-7.

The formation of dihydrodiols in the chemical or enzymic oxidation of dibenz[a,c]anthracene, dibenz[a,h]-anthracene and chrysene.二苯并[a,c]蒽、二苯并[a,h]蒽和芘在化学或酶促氧化过程中形成二氢二醇。

Chem Biol Interact. 1979 Oct;27(2-3):365-79. doi: 10.1016/0009-2797(79)90139-x.

Metabolic conversion of dibenz[a,h]anthracene (+/-)trans-1,2-dihydrodiol and chrysene (+/-)trans-3,4-dihydrodiol to vicinal dihydrodiol epoxides.二苯并[a,h]蒽（±）反式-1,2-二氢二醇和屈（±）反式-3,4-二氢二醇向邻位二氢二醇环氧化物的代谢转化。

Proc Natl Acad Sci U S A. 1981 Jul;78(7):4270-3. doi: 10.1073/pnas.78.7.4270.

Interactions of the K-region epoxides of phenanthrene and dibenz (a,h)anthracene with nucleic acids and histone.菲和二苯并（a，h）蒽的K区域环氧化物与核酸和组蛋白的相互作用。

Biochem Pharmacol. 1970 Jul;19(7):2251-9. doi: 10.1016/0006-2952(70)90124-3.

Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes.人肝微粒体中环氧化物水解酶对芳烃氧化物和烯烃氧化物的水化作用。

Clin Pharmacol Ther. 1977 Feb;21(2):158-65. doi: 10.1002/cpt1977212158.

Metabolism of the bay-region diol-epoxide of chrysene to a triol-epoxide and the enzyme-catalysed conjugation of these epoxides with glutathione.苯并[a]芘的湾区二醇环氧化物代谢为三醇环氧化物以及这些环氧化物与谷胱甘肽的酶催化缀合反应。

Carcinogenesis. 1986 Dec;7(12):2095-8. doi: 10.1093/carcin/7.12.2095.

Epoxy derivatives of aromatic polycyclic hydrocarbons. The synthesis of dibenz[a,c]anthracene 10,11-oxide and its metabolism by rat liver preparations.芳香多环烃的环氧衍生物。二苯并[a,c]蒽10,11-氧化物的合成及其在大鼠肝脏制剂中的代谢。

Biochem J. 1972 Nov;130(1):27-35. doi: 10.1042/bj1300027.

Metabolism of chrysene and phenanthrene to bay-region diol epoxides by rat liver enzymes.大鼠肝脏酶将屈和菲代谢为湾区二醇环氧化物。

Mol Pharmacol. 1981 Jan;19(1):168-78.

Studies on the hepatic microsomal metabolism of (14C) phenanthrene.（14C）菲的肝微粒体代谢研究。

Biochem Pharmacol. 1978;27(14):1865-71. doi: 10.1016/0006-2952(78)90034-5.

Metabolism of (-)-trans-(3R, 4R)-dihydroxy-3,4-dihydrochrysene to diol epoxides by liver microsomes.肝脏微粒体将(-)-反式-(3R, 4R)-二羟基-3,4-二氢 Chrysene 代谢为二醇环氧化物。

Biochem Biophys Res Commun. 1981 Feb 27;98(4):961-9. doi: 10.1016/0006-291x(81)91204-3.

引用本文的文献

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation of benz( )anthracene 8,9-oxide and 10,11-dihydrobenz( )anthracene 8,9-oxide and their metabolism by rat liver preparations.芳香多环烃的环氧衍生物。苯并（）蒽8,9 - 氧化物和10,11 - 二氢苯并（）蒽8,9 - 氧化物的制备及其在大鼠肝脏制剂中的代谢。

Biochem J. 1971 Nov;125(1):159-68. doi: 10.1042/bj1250159.

Formation of epoxides as microsomal metabolites of polycyclic hydrocarbons.环氧化物作为多环烃微粒体代谢产物的形成。

Biochem J. 1971 Nov;125(2):28P. doi: 10.1042/bj1250028pa.

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to benzo(a)pyrene and to 7,8- and 9,10-dihydrobenzo(a)pyrene.芳香多环烃的环氧衍生物。与苯并(a)芘以及7,8-和9,10-二氢苯并(a)芘相关的环氧化物的制备与代谢。

Biochem J. 1972 Jun;128(2):265-77. doi: 10.1042/bj1280265.

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to 7,12-dimethylbenz(a)anthracene.芳香多环烃的环氧衍生物。与7,12-二甲基苯并(a)蒽相关的环氧化物的制备与代谢。

Biochem J. 1973 Feb;131(2):405-13. doi: 10.1042/bj1310405.

Biochem J. 1972 Nov;130(1):27-35. doi: 10.1042/bj1300027.

The metabolism of 7,12-dimethylbenz (a) anthracene by homogenates of the stomach and small intestine of mice.7,12-二甲基苯并(a)蒽在小鼠胃和小肠匀浆中的代谢情况。

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1971;76(3):223-30. doi: 10.1007/BF00303567.

Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds.芳烃氧化物与NIH迁移：芳香族化合物的代谢、毒性及致癌性

Experientia. 1972 Oct 15;28(10):1129-49. doi: 10.1007/BF01946135.

In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons.多环烃K区域衍生物对啮齿动物细胞的体外转化

Proc Natl Acad Sci U S A. 1971 Jun;68(6):1098-101. doi: 10.1073/pnas.68.6.1098.

Metabolism of phenanthrene by the marine cyanobacterium Agmenellum quadruplicatum PR-6.海洋蓝细菌四倍体聚球藻PR-6对菲的代谢作用

Appl Environ Microbiol. 1992 Apr;58(4):1351-9. doi: 10.1128/aem.58.4.1351-1359.1992.

A radiochemical assay for glycine N-acyltransferase activity. Some properties of the enzyme in rat and rabbit.甘氨酸N-酰基转移酶活性的放射化学测定。大鼠和家兔体内该酶的一些特性。

Biochem J. 1978 May 15;172(2):285-91. doi: 10.1042/bj1720285.

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