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特发性交通性脑积水:分流术后脑室大小的预后意义

Idiopathic communicating hydrocephalus: the prognostic significane of ventricular size after shunting.

作者信息

Millingen K S

出版信息

Clin Exp Neurol. 1979;16:167-74.

PMID:550938
Abstract

A description is given of the dramatic, sustained recovery of 3 demented and neurologically disable patients with idiopathic communicating hydrocephalus after they underwent ventriculo-atrial shunting. In those patients there was no significant change in ventricular size after the ventriculo-atrial shunting. 1 of the patients also had cortical atrophy. Hypertensive vasculopathy and multiple infarcts may be the explanation in 2 of the patients. Reveiw of the literature results in the following conclusions: 1) the CAT scan alone, perhaps combined with intrathecal "Amipaque' cisternography, provides the maximum information with the last trauma and may assist in the selection of patients for shunting. 2) Test removal of 20 to 30ml of CSF may be as satisfactory as pressure monitoring and infusion techniques in the prediction of successful shunting. The following do not have a reliable predictive value: a) The presence of cortical atrophy (shunting may sometimes be effective in mild to moderate cortical atrophy) b) The period of onset of symptoms c) The ventricular size before shunting and its alteration after shunting.

摘要

本文描述了3例患有特发性交通性脑积水的痴呆和神经功能障碍患者在接受脑室-心房分流术后戏剧性的、持续的康复情况。在这些患者中,脑室-心房分流术后脑室大小无明显变化。其中1例患者还存在皮质萎缩。2例患者的病因可能是高血压性血管病变和多发性梗死。文献回顾得出以下结论:1)单独的计算机断层扫描(CAT扫描),或许结合鞘内注入“阿米培克”脑池造影,能在创伤最小的情况下提供最多信息,并有助于选择适合分流术的患者。2)抽取20至30毫升脑脊液进行试验性引流,在预测分流术成功方面可能与压力监测和注入技术一样令人满意。以下因素不具有可靠的预测价值:a)皮质萎缩的存在(轻度至中度皮质萎缩时分流术有时可能有效);b)症状出现的时间;c)分流术前的脑室大小及其分流术后的变化。

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