Bray J, Craggs R
J Reprod Immunol. 1979 Jul;1(2):109-15. doi: 10.1016/0165-0378(79)90011-1.
Using an EA rosetting technique on cells from the rat metrial gland at days 12--15 of pregnancy, approximately 30% of the cells were found to possess immunoglobulin (Fc) receptors. At dat 14 a comparison was made between cells from the metrial gland and cells from the peritoneal exudate; binding affinity of each for homologous and heterologous immunoglobulins was assessed by the resulting inhibition of rosette formation. Cells from the metrial gland were inhibited to a greater degree than cells from the peritoneal exudate by low concentrations of rabbit, human and rat immunoglobulin. The Fc receptors observed on cells from the metrial gland show some resemblance to those described by other workers on yolk sac cells and certain foetal placental cells, but their function is at present unknown.
在妊娠第12至15天,运用EA玫瑰花结技术对大鼠子宫腺细胞进行检测,发现约30%的细胞具有免疫球蛋白(Fc)受体。在第14天,对子宫腺细胞和腹腔渗出液中的细胞进行了比较;通过检测玫瑰花结形成的抑制情况,评估了它们对同源和异源免疫球蛋白的结合亲和力。低浓度的兔、人及大鼠免疫球蛋白对子宫腺细胞的抑制程度大于腹腔渗出液中的细胞。在子宫腺细胞上观察到的Fc受体与其他研究者在卵黄囊细胞和某些胎儿胎盘细胞上描述的受体有一些相似之处,但其功能目前尚不清楚。