Jenkins R L, Parsons O A
Curr Alcohol. 1979;7:229-37.
Recovery of cognitive functioning in male alcoholic patients during 3 months abstinence was assessed using a shortened version of the Wisconsin Card Sorting Test (WCST). Twenty-four alcoholic patients were tested after 2 to 3 weeks of sobriety and at 11 to 12 weeks post-drinking, while a second group of 24 alcoholic patients was tested only after 11 to 12 weeks of sobriety. A control group of 24 healthy males also received the WCST. After 3 weeks of sobriety, alcoholic patients completed significantly fewer categories and made more errors than control subjects. Alcoholic patients also made more perseverative response than did controls. At 12 weeks post-drinking, the performance of alcoholic subjects was intermediate to that of controls and to alcoholic patients tested following 3 weeks of abstinence and did not differ significantly from either group. The results suggest that following the acute withdrawal period alcoholic patients experience difficulties in conceptual abilities and in the capacity to shift cognitive sets when appropriate. After nearly 3 months of abstinence, partial but not complete recovery of these abilities is evident.
使用威斯康星卡片分类测验(WCST)的简化版,评估男性酒精性患者在戒酒3个月期间认知功能的恢复情况。24名酒精性患者在戒酒2至3周后以及戒酒11至12周后接受测试,而另一组24名酒精性患者仅在戒酒11至12周后接受测试。24名健康男性组成的对照组也接受了WCST测试。戒酒3周后,酒精性患者完成的类别显著少于对照组,且错误更多。酒精性患者的持续性反应也比对照组更多。在戒酒12周后,酒精性患者的表现介于对照组和戒酒3周后接受测试的酒精性患者之间,且与两组均无显著差异。结果表明,在急性戒断期后,酒精性患者在概念能力以及在适当的时候转换认知集的能力方面存在困难。经过近3个月的戒酒,这些能力有部分但未完全恢复。