Dinse H R, Fallert M, Böhmer G
Arch Ital Biol. 1979 Jan;117(1):23-9.
Three metabolic modifiers of the PFK-HDPase system were applied to bulbar respiratory neurons and, for comparison, also to unspecific cells. F-6-P did not alter the spike density of the majority of the respiratory and about half of the unspecific neurons. When responding, IE units were activated and unspecific cells were inhibited. Citrate did not alter the spike density of about half of all neurons tested. When responding, excitation prevailed in IE and E units, while unspecific cells were inhibited. AMP did not alter the spike density of the majority of the respiratory and about half of the unspecific cells. When responding, I neurons were activated, inhibition preponderated in IE units and both effects occurred in unspecific cells. The large number of zero effects suggests that the activity of only part of the cells is governed by the PFK-HDPase system.
三种磷酸果糖激酶-1，6-二磷酸酶（PFK-HDPase）系统的代谢调节剂被应用于延髓呼吸神经元，并且为了进行比较，也被应用于非特异性细胞。6-磷酸果糖（F-6-P）并没有改变大多数呼吸神经元以及大约一半非特异性神经元的放电密度。在有反应时，吸气-呼气（IE）单位被激活，而非特异性细胞受到抑制。柠檬酸没有改变大约一半测试神经元的放电密度。在有反应时，IE和呼气（E）单位以兴奋为主，而非特异性细胞受到抑制。腺苷一磷酸（AMP）并没有改变大多数呼吸细胞以及大约一半非特异性细胞的放电密度。在有反应时，抑制性（I）神经元被激活，IE单位以抑制为主，两种效应在非特异性细胞中均有发生。大量的零效应表明只有部分细胞的活动受PFK-HDPase系统调控。
