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Pigment formation for differentiating Cryptococcus neoformans from Candida albicans.用于区分新型隐球菌和白色念珠菌的色素形成。
Appl Microbiol. 1971 Mar;21(3):541-2. doi: 10.1128/am.21.3.541-542.1971.
2
Pigment production of Cryptococcus neoformans grown with extracts of Guizotia abyssinica.用阿比西尼亚帚菊提取物培养新型隐球菌的色素生成
Appl Microbiol. 1971 Sep;22(3):478-9. doi: 10.1128/am.22.3.478-479.1971.
3
Pigment production by Cryptococcus neoformans from para- and ortho-Diphenols: effect of the nitrogen source.新型隐球菌利用对二酚和邻二酚产生色素：氮源的影响。
J Clin Microbiol. 1975 Jun;1(6):509-14. doi: 10.1128/jcm.1.6.509-514.1975.
4
Pigmentation and autofluorescence of Cryptococcus species after growth on tryptophan and anthranilic acid media.在色氨酸和邻氨基苯甲酸培养基上生长后隐球菌属的色素沉着和自发荧光
Mycopathologia. 1978 Oct 16;64(2):105-12. doi: 10.1007/BF00440970.
5
Growth and pigment production on D-tryptophan medium by Cryptococcus gattii, Cryptococcus neoformans, and Candida albicans.加氏隐球菌、新生隐球菌和白色念珠菌在D-色氨酸培养基上的生长及色素产生情况。
J Clin Microbiol. 2008 Jan;46(1):255-64. doi: 10.1128/JCM.01721-07. Epub 2007 Nov 7.
6
[Cryptococcus neoformans: pigment formation on polyphenols].
Med Microbiol Immunol. 1971;157(1):46-51. doi: 10.1007/BF02121290.
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New culture medium for the presumptive identificaion of Candida albicans and Cryptococcus neoformans.用于白色念珠菌和新型隐球菌初步鉴定的新型培养基。
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Further simplification of the Guizotia abyssinica seed medium for identification of Cryptococcus neoformans and Cryptococcus bacillispora.用于新型隐球菌和芽孢隐球菌鉴定的埃塞俄比亚芥籽培养基的进一步简化
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Evaluation of a simplified Guizotia abyssinica seed medium for differentiation of Cryptococcus neoformans.一种用于新型隐球菌鉴别的简化埃塞俄比亚芥籽培养基的评估
J Clin Microbiol. 1978 Apr;7(4):346-8. doi: 10.1128/jcm.7.4.346-348.1978.
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Isolation of Cryptococcus neoformans from pigeon manure on two media inducing pigment formation.在两种诱导色素形成的培养基上从鸽粪中分离新型隐球菌。
Sabouraudia. 1982 Sep;20(3):193-7.

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Histoplasma capsulatum synthesizes melanin-like pigments in vitro and during mammalian infection.荚膜组织胞浆菌在体外和哺乳动物感染期间会合成类黑色素色素。
Infect Immun. 2002 Sep;70(9):5124-31. doi: 10.1128/IAI.70.9.5124-5131.2002.
2
Pathogenic roles for fungal melanins.真菌黑色素的致病作用。
Clin Microbiol Rev. 2000 Oct;13(4):708-17. doi: 10.1128/CMR.13.4.708.
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Infect Immun. 1995 Dec;63(12):4944-5. doi: 10.1128/iai.63.12.4944-4945.1995.
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A DL-DOPA drop test for the identification of Cryptococcus neoformans.用于鉴定新型隐球菌的DL-多巴滴度试验。
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8
[Cryptococcus neoformans: pigment formation on polyphenols].
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9
Production of diagnostic pigment by phenoloxidase activity of cryptococcus neoformans.新型隐球菌酚氧化酶活性产生诊断色素。
Appl Microbiol. 1972 Nov;24(5):824-30. doi: 10.1128/am.24.5.824-830.1972.
10
Pigment production by Cryptococcus neoformans from para- and ortho-Diphenols: effect of the nitrogen source.新型隐球菌利用对二酚和邻二酚产生色素：氮源的影响。
J Clin Microbiol. 1975 Jun;1(6):509-14. doi: 10.1128/jcm.1.6.509-514.1975.

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[ON A CULTURE MEDIUM CONTAINING QUINIC ACID FOR THE DIFFERENTIATION AND ENRICHMENT OF PSEUDOMONAS AERUGINOSA].[在含有奎尼酸的培养基上用于铜绿假单胞菌的分化和富集]
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[MEMBRANE FILTRATION AND GUIZOTIA ABYSSINICA CULTURE MEDIA FOR THE DEMONSTRATION OF CRYPTOCOCCUS NEOFORMANS (BROWN COLOR EFFECT)].[用于新型隐球菌（棕色效应）检测的膜过滤法与埃塞俄比亚芥培养基]
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The production of an N-acylanthranilic acid from shikimic acid and the effect on iron deficiency on the biosynthesis of other aromatic compounds by Aerobacter aerogenes.
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Medium for selective isolation of Cryptococcus neoformans.新型隐球菌的选择性分离培养基。
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A survey to determine the occurrence of Histoplasma capsulatum and Cryptococcus neoformans in air-conditioners.一项旨在确定空调中荚膜组织胞浆菌和新型隐球菌存在情况的调查。
Mycopathol Mycol Appl. 1969 May 28;37(4):372-6. doi: 10.1007/BF02129885.
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Modified Littman oxgall agar to isolate Cryptococcus neoformans.改良利特曼牛胆汁琼脂用于分离新型隐球菌。
Appl Microbiol. 1968 May;16(5):689-90. doi: 10.1128/am.16.5.689-690.1968.
8
[2,3-dihydroxybenzoic acid and its amino acid derivatives in the culture medium of Klebsiella oxytoca].[产酸克雷伯菌培养基中的2,3-二羟基苯甲酸及其氨基酸衍生物]
Arch Mikrobiol. 1970;70(3):297-302.

用于区分新型隐球菌和白色念珠菌的色素形成。

Pigment formation for differentiating Cryptococcus neoformans from Candida albicans.

作者信息

Korth H, Pulverer G

出版信息

Appl Microbiol. 1971 Mar;21(3):541-2. doi: 10.1128/am.21.3.541-542.1971.

DOI:10.1128/am.21.3.541-542.1971
PMID:5553288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC377219/
Abstract

When 2,3- or 3,4-dihydroxybenzoic acid, 3,4-dihydroxyphenylalanine, and 3,4-dihydroxycinnamic acid are added to growth media, they are converted to a characteristic brown pigment by Cryptococcus neoformans. This pigment formation has hitherto been encountered only when this microorganism was cultivated on media containing Guizotia abyssinica seed. This phenomenon can be used for differentiating Cryptococcus neoformans from Candida albicans. Possible precursors of these o-diphenols (quinic acid, aromatic monohydroxy acids, or tyrosine) do not give rise to the brown pigmentation.

摘要

当将2,3 - 或3,4 - 二羟基苯甲酸、3,4 - 二羟基苯丙氨酸和3,4 - 二羟基肉桂酸添加到生长培养基中时，新型隐球菌会将它们转化为一种特征性的棕色色素。迄今为止，只有当这种微生物在含有埃塞俄比亚画眉草种子的培养基上培养时，才会出现这种色素形成现象。这种现象可用于区分新型隐球菌和白色念珠菌。这些邻二酚的可能前体（奎尼酸、芳香单羟基酸或酪氨酸）不会产生棕色色素沉着。