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Infect Immun. 1995 Dec;63(12):4944-5. doi: 10.1128/iai.63.12.4944-4945.1995.
2
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本文引用的文献

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The free radical property of melanins.黑色素的自由基特性。
Arch Biochem Biophys. 1960 Feb;86:225-30. doi: 10.1016/0003-9861(60)90409-4.
2
Gene cluster involved in melanin biosynthesis of the filamentous fungus Alternaria alternata.参与丝状真菌链格孢黑色素生物合成的基因簇。
J Bacteriol. 1993 Jul;175(14):4427-35. doi: 10.1128/jb.175.14.4427-4435.1993.
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Antioxidant function of fungal melanin.真菌黑色素的抗氧化功能。
J Bacteriol. 1993 Nov;175(21):7102-4. doi: 10.1128/jb.175.21.7102-7104.1993.
4
Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants.黑色素化和非黑色素化新型隐球菌对氮源和氧源氧化剂的敏感性。
Infect Immun. 1994 Jul;62(7):3004-7. doi: 10.1128/iai.62.7.3004-3007.1994.
5
Cryptococcus neoformans melanin and virulence: mechanism of action.新型隐球菌黑色素与毒力:作用机制
Infect Immun. 1995 Aug;63(8):3131-6. doi: 10.1128/iai.63.8.3131-3136.1995.
6
Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice.新型隐球菌缺乏黑色素的突变体及其对小鼠的毒力。
J Bacteriol. 1982 Jun;150(3):1414-21. doi: 10.1128/jb.150.3.1414-1421.1982.
7
Pentaketide metabolites of melanin synthesis in the dematiaceous fungus Wangiella dermatitidis.暗色丝孢霉病真菌皮炎外瓶霉中黑色素合成的戊糖代谢物
Arch Microbiol. 1984 Apr;137(4):324-8. doi: 10.1007/BF00410729.
8
Hydrogen peroxide metabolism in human monocytes during differentiation in vitro.体外分化过程中人类单核细胞中的过氧化氢代谢
J Clin Invest. 1981 Nov;68(5):1243-52. doi: 10.1172/jci110370.
9
Pigment formation for differentiating Cryptococcus neoformans from Candida albicans.用于区分新型隐球菌和白色念珠菌的色素形成。
Appl Microbiol. 1971 Mar;21(3):541-2. doi: 10.1128/am.21.3.541-542.1971.
10
A study of the oxidation-reduction state of synthetic 3,4-dihydroxy-DL-phenylalanine melanin.合成3,4-二羟基-DL-苯丙氨酸黑色素氧化还原状态的研究
Mol Pharmacol. 1971 Jul;7(4):429-33.

黑色素在黑色真菌中的抗氧化功能。

Antioxidant function of melanin in black fungi.

作者信息

Jacobson E S, Hove E, Emery H S

机构信息

McGuire Veterans Affairs Medical Center, Richmond, Virginia, USA.

出版信息

Infect Immun. 1995 Dec;63(12):4944-5. doi: 10.1128/iai.63.12.4944-4945.1995.

DOI:10.1128/iai.63.12.4944-4945.1995
PMID:7591162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC173711/
Abstract

1,8-Dihydroxynaphthalene melanin in Wangiella dermatitidis and Alternaria alternata was titrated in vivo with the oxidants permanganate, hypochlorite, and H2O2. Melanized strains neutralized more oxidant and withstood higher concentrations of permanganate and hypochlorite than albino strains did. H2O2 killing required 1,000-fold higher concentrations, and melanin did not protect W. dermatitidis against H2O2.

摘要

用氧化剂高锰酸盐、次氯酸盐和过氧化氢对皮炎万吉拉霉和链格孢中的1,8 - 二羟基萘黑色素进行体内滴定。与白化菌株相比,黑色素化菌株中和了更多的氧化剂,并且能耐受更高浓度的高锰酸盐和次氯酸盐。过氧化氢杀菌所需浓度要高1000倍,黑色素并不能保护皮炎万吉拉霉免受过氧化氢的伤害。