在注射低剂量卵清蛋白的小鼠中持续形成反应素。
Persistent formation of reagins in mice injected with low doses of ovalbuminl.
作者信息
Vaz E M, Vaz N M, Levine B B
出版信息
Immunology. 1971 Jul;21(1):11-5.
Abstract
Immunization of mice with minute doses (0.1 μg) of ovalbumin in A1(OH) gel induced persistent synthesis of high titres (1:160, 1:320) of reaginic and IgG1 antibodies. Immunization with high doses of ovalbumin (100 μg) induced high IgG1 titres but only weak and transient formation of reagins. Inbred mouse strains differ widely in their immune responsiveness to low doses of ovalbumin.
摘要
用微量（0.1μg）卵清蛋白在氢氧化铝凝胶中免疫小鼠，可诱导产生高滴度（1:160, 1:320）的反应素和IgG1抗体的持续合成。用高剂量（100μg）卵清蛋白免疫可诱导产生高IgG1滴度，但仅产生微弱且短暂的反应素形成。近交系小鼠品系对低剂量卵清蛋白的免疫反应性差异很大。
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