口服免疫对异源抗原局部和全身免疫反应的影响。
The influence of oral immunization on local and systemic immune responses to heterologous antigens.
作者信息
Stokes C R, Newby T J, Bourne F J
出版信息
Clin Exp Immunol. 1983 May;52(2):399-406.
Abstract
Oral immunization with 25 mg/day of ovalbumin resulted in a number of changes in non-specific immune responsiveness, including increases in antibody produced to T-dependent but not T-independent antigens and the abrogation of tolerance induced by both oral and intravenous routes. The effect was transient, sex- and strain-dependent. Evidence suggests that it is a consequence of cell-mediated immunity to the oral immunogen.
摘要
每天口服25毫克卵清蛋白会导致非特异性免疫反应发生一系列变化，包括针对T细胞依赖性而非T细胞非依赖性抗原产生的抗体增加，以及口服和静脉途径诱导的耐受性被消除。这种效应是短暂的，具有性别和品系依赖性。有证据表明，这是对口服免疫原的细胞介导免疫的结果。
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