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噬菌体φX174超感染排除对蛋白质合成的需求。

Requirement of protein synthesis for bacteriophage phi X174 superinfection exclusion.

作者信息

Hutchison C A, Sinsheimer R L

出版信息

J Virol. 1971 Jul;8(1):121-4. doi: 10.1128/JVI.8.1.121-124.1971.

Abstract

Within 5 to 10 min at 37 C, bacteria infected by bacteriophage phiX174 acquire the ability to exclude superinfecting phiX particles from reproducing themselves. The superinfecting phage are blocked at a stage prior to synthesis of the parental replicative form molecule; the superinfecting deoxyribonucleic acid remains as intact (infective) single strands. Establishment of superinfection exclusion and its maintenance require protein synthesis.

摘要

在37摄氏度下5到10分钟内,被噬菌体phiX174感染的细菌获得了阻止超感染的phiX颗粒自我繁殖的能力。超感染的噬菌体在亲本复制形式分子合成之前的阶段被阻断;超感染的脱氧核糖核酸保持完整(有感染性)的单链状态。建立和维持超感染排除需要蛋白质合成。

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