Skidmore F D
Teratology. 1977 Feb;15(1):97-102. doi: 10.1002/tera.1420150113.
The crown-rump length of 483 fixed human embryos of Carnegie stages 6-23 was analyzed and median and predicted mean lengths were calculated. The results were compared with those of other series and confirmed that early human growth rates are different from those of macaques with which human embryo growth has previously been compared. The study indicated that it is possible to predict: 1. the median size of an embryo of given Streeter horizon or Carnegie stage; 2. the age of a fresh embryo, or one of undisputed Streeter staging, by comparison with mean figures of other authorities; and 3. the corrected age of an embryo of known length or known Streeter staging or both in terms of postovulation age. Since teratogens may reduce the embryonic growth rate this information is relevant in the analysis of teratogenic factors in human development.
对483个处于卡内基第6至23期的固定人类胚胎的冠臀长度进行了分析，并计算了中位数长度和预测平均长度。将结果与其他系列的结果进行比较，证实人类早期生长速率与先前用于比较人类胚胎生长的猕猴不同。该研究表明，可以预测：1. 处于特定斯特里特分期或卡内基期的胚胎的中位数大小；2. 通过与其他权威机构的平均数据比较，预测新鲜胚胎或分期明确的胚胎的年龄；3. 根据排卵后年龄，预测已知长度或已知斯特里特分期或两者皆有的胚胎的校正年龄。由于致畸剂可能会降低胚胎生长速率，因此这些信息在分析人类发育中的致畸因素时具有重要意义。
