Wilkie F, Eisdorfer C
Science. 1971 May 28;172(3986):959-62. doi: 10.1126/science.172.3986.959.
Diastolic hypertension was related to significant intellectual loss over a 10-year period among individuals initially examined in their 60's. Such loss was not found in their age peers in association with normal or mild elevations of blood pressure. Of the subjects initially examined at 70 to 79 years of age, none with hypertension completed the follow-up program, and those with normal and mildly elevated blood pressure showed some intellectual decline over the decade. At the initial examination, hypertension was related to lower intelligence test scores only among those subjects who subsequently did not complete the follow-up program. The results suggest that hypertension is related to intellectual changes among the aged.
舒张期高血压与60多岁开始接受初次检查的个体在10年期间智力显著下降有关。在血压正常或轻度升高的同龄人中未发现这种智力下降情况。在70至79岁开始接受初次检查的受试者中，没有高血压患者完成随访计划，而血压正常和轻度升高的患者在这十年中出现了一些智力衰退。在初次检查时，高血压仅与那些随后未完成随访计划的受试者智力测试得分较低有关。研究结果表明，高血压与老年人的智力变化有关。
