Horten B C, Urich H, Rubinstein L J, Montague S R
J Neurol Sci. 1977 Apr;31(3):387-410. doi: 10.1016/0022-510x(77)90217-9.
The validity of the concept of the angioblastic meningioma, now in dispute, was reexamined by reviewing 79 meningeal and angioblastic tumors of the central nervous system and by comparing the fine structural characteristics and in vitro evolution of 2 typical meningiomas and 1 intracranial hemangiopericytoma. While most tumors show the consistent features of either hemangiopericytoma or hemangioblastoma, there exist transitional forms between these tumors and typical meningioma. There is also a greater degree of morphological overlap at the electron microscopic level than has been recognized up till now. In view of these findings the concept of the angioblastic meningioma deserves to be retained as a generic term to include craniospinal hemangiopericytomas and transitional forms between hemangiopericytoma, hemangioblastoma and classic meningioma. It is postulated that all these tumors share a common origin from polyblastic mesenchymal cells originating in or derived from the meninges.
通过回顾79例中枢神经系统的脑膜瘤和血管母细胞性肿瘤，并比较2例典型脑膜瘤和1例颅内血管外皮细胞瘤的精细结构特征及体外演变过程，对目前存在争议的血管母细胞性脑膜瘤这一概念的有效性进行了重新审视。虽然大多数肿瘤呈现出血管外皮细胞瘤或成血管细胞瘤的一致特征，但在这些肿瘤与典型脑膜瘤之间存在过渡形式。在电子显微镜水平上，形态学重叠的程度也比迄今所认识到的更大。鉴于这些发现，血管母细胞性脑膜瘤这一概念值得保留，作为一个通用术语，包括颅脊髓血管外皮细胞瘤以及血管外皮细胞瘤、成血管细胞瘤和经典脑膜瘤之间的过渡形式。据推测，所有这些肿瘤都起源于起源于脑膜或源自脑膜的多胚层间充质细胞。
