人骨髓淋巴细胞中的末端转移酶。
Terminal transferase in human bone-marrow lymphocytes.
作者信息
Barr R D, Sarin P S, Perry S M
出版信息
Lancet. 1976 Mar 6;1(7958):508-9. doi: 10.1016/s0140-6736(76)90295-6.
PMID:55782
Abstract
Activity of the enzyme terminal transferase (TdT) has been localised in normal human bone-marrow lymphocytes. These cells may represent a prothymocyte population, which, on malignant transformation, may give rise to acute lymphoblastic leukaemia, and to some cases of chronic granulocytic leukaemia in the blastic phase.
摘要
末端转移酶（TdT）的活性已定位在正常人骨髓淋巴细胞中。这些细胞可能代表原胸腺细胞群体，在恶性转化时，可能引发急性淋巴细胞白血病以及某些急变期慢性粒细胞白血病病例。
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