Strauchen J A
West J Med. 1981 Oct;135(4):276-84.
Identification of cell surface markers permits detailed analysis and classification of the cells involved in the immune response. Application of these techniques to the study of malignant lymphomas has led to our understanding of these tumors as neoplasms of specific elements of the immune system. This approach, which emphasizes functional characteristics of the neoplastic cells, promises to revolutionize the diagnosis and classification of the lymphomas and replace classifications based solely on morphology.
细胞表面标志物的鉴定有助于对免疫反应中涉及的细胞进行详细分析和分类。将这些技术应用于恶性淋巴瘤的研究,使我们将这些肿瘤理解为免疫系统特定成分的肿瘤。这种强调肿瘤细胞功能特征的方法有望彻底改变淋巴瘤的诊断和分类,并取代仅基于形态学的分类方法。