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恶性淋巴瘤:细胞表面标志物与分类进展

Malignant lymphomas: cell surface markers and advances in classification.

作者信息

Strauchen J A

出版信息

West J Med. 1981 Oct;135(4):276-84.

Abstract

Identification of cell surface markers permits detailed analysis and classification of the cells involved in the immune response. Application of these techniques to the study of malignant lymphomas has led to our understanding of these tumors as neoplasms of specific elements of the immune system. This approach, which emphasizes functional characteristics of the neoplastic cells, promises to revolutionize the diagnosis and classification of the lymphomas and replace classifications based solely on morphology.

摘要

细胞表面标志物的鉴定有助于对免疫反应中涉及的细胞进行详细分析和分类。将这些技术应用于恶性淋巴瘤的研究,使我们将这些肿瘤理解为免疫系统特定成分的肿瘤。这种强调肿瘤细胞功能特征的方法有望彻底改变淋巴瘤的诊断和分类,并取代仅基于形态学的分类方法。

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本文引用的文献

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Br J Surg. 1958 Nov;46(197):218-23. doi: 10.1002/bjs.18004619704.
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Contamination of Hodgkin's disease cell cultures.霍奇金病细胞培养物的污染
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Immunologic characterization of human malignant lymphomas.人类恶性淋巴瘤的免疫学特征
Cancer. 1974 Oct;34(4 Suppl):suppl:1488-503. doi: 10.1002/1097-0142(197410)34:8+<1488::aid-cncr2820340822>3.0.co;2-c.

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