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洗涤剂毒性调查。

Detergent toxicity survey.

作者信息

Seabaugh V M, Bayard S P, Osterberg R E, Porter W K, McCaulley D F, Hoheisel C A, Hehir R M, Bierbower G W

出版信息

Am J Public Health. 1977 Apr;67(4):367-9. doi: 10.2105/ajph.67.4.367.

DOI:10.2105/ajph.67.4.367
PMID:557906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1653623/
Abstract

A survey of over 249 detergent products involving biological testing, chemical analyses, and product label reviews has been conducted from 1971-1976 for determining compliance with the Federal Hazardous Substances Act. Test results for 145 detergent products having both chemical and biological data were examined. All of the tested detergents were rabbit eye irritants. Forty-seven per cent were also either rabbit primary skin irritants or corrosives. Eighty-one per cent were either rabbit esophageal test irritants or corrosives, and 80 per cent had rat oral toxicities 5g/kg or less.

摘要

1971年至1976年期间,为确定是否符合《联邦有害物质法》,对249种以上的洗涤剂产品进行了一项涉及生物测试、化学分析和产品标签审查的调查。对145种既有化学数据又有生物数据的洗涤剂产品的测试结果进行了检查。所有测试的洗涤剂对兔子眼睛都有刺激性。47%的产品对兔子皮肤也是原发性刺激物或具有腐蚀性。81%的产品对兔子食管测试有刺激性或具有腐蚀性,80%的产品对大鼠经口毒性为5克/千克或更低。

相似文献

1
Detergent toxicity survey.洗涤剂毒性调查。
Am J Public Health. 1977 Apr;67(4):367-9. doi: 10.2105/ajph.67.4.367.
2
Eye irritation responses in rabbit and man after single applications of equal volumes of undiluted model liquid detergent products.单次等量使用未稀释的模型液体洗涤剂产品后,兔子和人类的眼睛刺激反应。
Food Chem Toxicol. 2000 Aug;38(8):727-34. doi: 10.1016/s0278-6915(00)00057-0.
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A rapid cell culture technique for assessing the toxicity of detergent-based products in vitro as a possible screen for eye irritancy in vivo.一种快速细胞培养技术,用于体外评估基于洗涤剂的产品的毒性,作为体内眼刺激性的一种可能筛选方法。
Cytobios. 1983;36(143-44):153-9.
4
An in vitro cytotoxicity test to predict the ocular irritation potential of detergents and detergent products.
Food Chem Toxicol. 1985 Feb;23(2):253-8. doi: 10.1016/0278-6915(85)90025-0.
5
Potential biological hazards of commercially available cleansers for dentures.市售假牙清洁剂的潜在生物危害。
J Toxicol Environ Health. 1977 Dec;3(5-6):969-77. doi: 10.1080/15287397709529631.
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Suitability of histopathology as an additional endpoint to the Isolated Chicken Eye Test for classification of non-extreme pH detergent and cleaning products.组织病理学作为孤立鸡眼试验的附加终点用于非极端pH值洗涤剂和清洁产品分类的适用性。
Toxicol In Vitro. 2014 Jun;28(4):657-66. doi: 10.1016/j.tiv.2014.01.010. Epub 2014 Feb 6.
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Suitability of the isolated chicken eye test for classification of extreme pH detergents and cleaning products.分离鸡眼试验用于极端pH值洗涤剂和清洁产品分类的适用性。
Toxicol In Vitro. 2015 Apr;29(3):609-16. doi: 10.1016/j.tiv.2014.12.020. Epub 2015 Jan 19.
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Drug Chem Toxicol. 1978;1(4):391-400. doi: 10.3109/01480547809016050.
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The rabbit as a model for evaluating skin irritants: a comparison of results obtained on animals and man using repeated skin exposures.作为评估皮肤刺激物模型的兔子:对动物和人类反复皮肤接触所得结果的比较。
Food Cosmet Toxicol. 1975 Oct;13(5):533-40. doi: 10.1016/0015-6264(75)90008-5.
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Zeolithe A--A phosphate substitute for detergents: toxicological investigation.沸石A——一种用于洗涤剂的磷酸盐替代品:毒理学研究。
Food Chem Toxicol. 1983 Apr;21(2):209-20. doi: 10.1016/0278-6915(83)90238-7.

本文引用的文献

1
Hazards of alkaline laundry detergents.碱性洗衣粉的危害。
JAMA. 1972 May 15;220(7):1014-5. doi: 10.1001/jama.1972.03200070102026.
2
Assessing detergent safety: a comparison of a nonphosphate laundry detergent with phosphate detergents.评估洗涤剂安全性:无磷洗衣粉与含磷洗衣粉的比较。
J Am Oil Chem Soc. 1972 Oct;49(10):539-51. doi: 10.1007/BF02609223.
3
Relative eye-injury potential of heavy-duty phosphate and non-phosphate laundry detergents.重型含磷和无磷洗衣粉的相对眼部损伤可能性。
Food Cosmet Toxicol. 1972 Dec;10(6):829-37. doi: 10.1016/s0015-6264(72)80009-9.
4
Corrosive injury of the stomach and esophagus by nonphosphate detergents. An experimental study.非磷酸盐洗涤剂所致胃和食管的腐蚀性损伤。一项实验研究。
Am J Surg. 1972 Jun;123(6):652-6. doi: 10.1016/0002-9610(72)90347-9.