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The separation of adenine and hypoxanthine-guanine phosphoribosyl transferases isoenzymes by disc gel electrophoresis.

作者信息

Bakay B, Nyhan W L

出版信息

Biochem Genet. 1971 Feb;5(1):81-90. doi: 10.1007/BF00485733.

DOI:10.1007/BF00485733
PMID:5582066
Abstract
摘要

相似文献

1
The separation of adenine and hypoxanthine-guanine phosphoribosyl transferases isoenzymes by disc gel electrophoresis.通过圆盘凝胶电泳分离腺嘌呤和次黄嘌呤 - 鸟嘌呤磷酸核糖基转移酶同工酶。
Biochem Genet. 1971 Feb;5(1):81-90. doi: 10.1007/BF00485733.
2
Electrophoretic properties of hypoxanthine-guanine phosphoribosyl transferase in erythrocytes of subjects with Lesch-Nyhan syndrome.莱施-奈恩综合征患者红细胞中次黄嘌呤-鸟嘌呤磷酸核糖转移酶的电泳特性
Biochem Genet. 1972 Apr;6(2):139-46. doi: 10.1007/BF00486398.
3
Isoenzymes of hypoxanthine-guanine-phosphoribosyl transferase in a family with partial deficiency of the enzyme.一个次黄嘌呤-鸟嘌呤磷酸核糖转移酶部分缺乏家族中的同工酶
Biochem Genet. 1972 Aug;7(1):73-85. doi: 10.1007/BF00487011.
4
Purification of IMP:pyrophosphate phosphoribosyltransferases, catalytically incompetent enzymes in Lesch-Nyhan disease.次黄嘌呤单磷酸：焦磷酸磷酸核糖基转移酶的纯化，莱施-奈恩病中的催化失活酶
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1461-4. doi: 10.1073/pnas.68.7.1461.
5
Resistance of erythrocyte adenine phosphoribosyltransferase in the Lesch-Nyhan syndrome to destabilization to heat by hypoxanthine.莱施-奈恩综合征中红细胞腺嘌呤磷酸核糖基转移酶对次黄嘌呤介导的热不稳定作用的抗性
Adv Exp Med Biol. 1973;41:215-20. doi: 10.1007/978-1-4684-3294-7_26.
6
Hypoxanthine-guanine phosphoribosyl transferase deficiency. Our experience.次黄嘌呤-鸟嘌呤磷酸核糖转移酶缺乏症。我们的经验。
Adv Exp Med Biol. 1973;41:271-9. doi: 10.1007/978-1-4684-3294-7_32.
7
Activation of variants of hypoxanthine-guanine phosphoribosyl transferase by the normal enzyme.正常酶对次黄嘌呤 - 鸟嘌呤磷酸核糖基转移酶变体的激活作用。
Proc Natl Acad Sci U S A. 1972 Sep;69(9):2523-6. doi: 10.1073/pnas.69.9.2523.
8
Heterogeneity in the biochemical characteristics of red blood cell hypoxanthine-guanine phosphoribosyl transferase from two unrelated patients with the Lesch-Nyhan syndrome.两名无关的莱施-奈恩综合征患者红细胞次黄嘌呤-鸟嘌呤磷酸核糖基转移酶生化特性的异质性。
Biochem Genet. 1973 Jun;9(2):197-202. doi: 10.1007/BF00487450.
9
Hypoxanthine-guanine phosphoribosyltransferase: characteristics of the mutant enzyme in erythrocytes from patients with the Lesch-Nyhan syndrome.次黄嘌呤-鸟嘌呤磷酸核糖转移酶：莱施-奈恩综合征患者红细胞中突变酶的特征
J Clin Invest. 1972 Jul;51(7):1805-12. doi: 10.1172/JCI106982.
10
[Isoenzymes of purine phosphoribosyltransferases in erythrocytes of Lesch-Nyhan patients (author's transl)].
Z Klin Chem Klin Biochem. 1974 Jan;12(1):28-32.

引用本文的文献

1
Characterization of the subunit composition of HGPRTase from human erythrocytes and cultured fibroblasts.人红细胞和培养成纤维细胞中次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶亚基组成的表征
Biochem Genet. 1980 Feb;18(1-2):1-19. doi: 10.1007/BF00504356.
2
Cotransfer of linked eukaryotic genes and efficient transfer of hypoxanthine phosphoribosyltransferase by DNA-mediated gene transfer.通过DNA介导的基因转移实现连锁真核基因的共转移及次黄嘌呤磷酸核糖基转移酶的高效转移。
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1583-7. doi: 10.1073/pnas.77.3.1583.
3
Hypoxanthine: guanine phosphoribosyltransferase mutants in Saccharomyces cerevisiae.

本文引用的文献

1
INHIBITION OF PRUINE PHOSPHORIBOSYLTRANSFERASES OF EHRLICH ASCITES-TUMOUR CELLS BY 6-MERCAPTOPURINE.6-巯基嘌呤对艾氏腹水癌细胞嘌呤磷酸核糖转移酶的抑制作用
Biochem J. 1965 Jan;94(1):64-70. doi: 10.1042/bj0940064.
2
A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION.一种尿酸代谢与中枢神经系统功能的家族性疾病。
Am J Med. 1964 Apr;36:561-70. doi: 10.1016/0002-9343(64)90104-4.
3
A new disorder of purine metabolism with behavioral manifestations.一种伴有行为表现的嘌呤代谢新紊乱症。
酿酒酵母中的次黄嘌呤：鸟嘌呤磷酸核糖转移酶突变体
Mol Gen Genet. 1983;191(3):407-12. doi: 10.1007/BF00425755.
4
The development of hypoxanthine-guanine phosphoribosyltransferase activity in man.人次黄嘌呤-鸟嘌呤磷酸核糖基转移酶活性的发育
Biochem J. 1971 Nov;125(2):36P. doi: 10.1042/bj1250036pa.
5
Isoenzymes of hypoxanthine-guanine-phosphoribosyl transferase in a family with partial deficiency of the enzyme.一个次黄嘌呤-鸟嘌呤磷酸核糖转移酶部分缺乏家族中的同工酶
Biochem Genet. 1972 Aug;7(1):73-85. doi: 10.1007/BF00487011.
6
Linkage relationships of X-linked enzymes glucose-6-phosphate dehydrogenase and hypoxanthine guanine phosphoribosyltransferase: recombination in female offspring of compound heterozygotes.X连锁酶葡萄糖-6-磷酸脱氢酶和次黄嘌呤鸟嘌呤磷酸核糖基转移酶的连锁关系：复合杂合子雌性后代中的重组
Am J Hum Genet. 1974 Jul;26(4):512-22.
7
Microscale isoelectric focusing studies of mouse and human hypoxanthine-guanine phosphoribosyl transferases.小鼠和人次黄嘌呤-鸟嘌呤磷酸核糖转移酶的微量等电聚焦研究
Biochem Genet. 1973 Jun;9(2):175-85. doi: 10.1007/BF00487447.
8
The spontaneous azaguanine-resistant mutants of diploid human fibroblasts.二倍体人成纤维细胞的自发氮鸟嘌呤抗性突变体。
Humangenetik. 1972;16(1):87-110. doi: 10.1007/BF00393992.
9
Molecular variation in relation to purine metabolism.与嘌呤代谢相关的分子变异
J Clin Pathol Suppl (R Coll Pathol). 1974;8:48-63.
10
Restoration of hypoxanthine phosphoribosyl transferase activity in mouse 1R cells after fusion with chick-embryo fibroblasts.与鸡胚成纤维细胞融合后小鼠1R细胞中次黄嘌呤磷酸核糖基转移酶活性的恢复。
Proc Natl Acad Sci U S A. 1973 Jul;70(7):1998-2002. doi: 10.1073/pnas.70.7.1998.
J Pediatr. 1969 Jan;74(1):20-7. doi: 10.1016/s0022-3476(69)80004-1.
4
Human hypoxanthine phosphoribosyltransferase. I. Purification, properties, and specificity.人次黄嘌呤磷酸核糖基转移酶。I. 纯化、性质及特异性
J Biol Chem. 1969 Mar 10;244(5):1263-70.
5
Hypoxanthine-guanine phosphoribosyltransferase: further evidence for the identity of the binding sites for hypoxanthine and guanine.
Can J Biochem. 1969 Jan;47(1):69-71. doi: 10.1139/o69-012.
6
Adenine phosphoribosyltransferase deficiency: a previously undescribed genetic defect in man.腺嘌呤磷酸核糖转移酶缺乏症：一种人类之前未被描述的基因缺陷。
J Clin Invest. 1968 Oct;47(10):2281-9. doi: 10.1172/JCI105913.
7
Disorder of purine metabolism due to partial deficiency of hypoxanthine-guanine phosphoribosyltransferase. A study of a family.
Am J Med. 1970 Feb;48(2):148-61. doi: 10.1016/0002-9343(70)90111-7.
8
An electrophoretic method for detecting hypoxanthine-guanine phosphoribosyl transferase variants.一种检测次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶变体的电泳方法。
Biochem Genet. 1969 Jun;3(3):299-302. doi: 10.1007/BF00521145.
9
An improved technique for the separation of glucose 6-phosphate dehydrogenase isoenzymes by disc electrophoresis on polyacrylamide gel.一种通过聚丙烯酰胺凝胶圆盘电泳分离6-磷酸葡萄糖脱氢酶同工酶的改良技术。
Biochem Genet. 1969 Dec;3(6):571-82. doi: 10.1007/BF00485478.
10
Hypoxanthine-guanine phosphoribosyltransferase deficiency in gout.痛风中的次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶缺乏症
Ann Intern Med. 1969 Jan;70(1):155-206. doi: 10.7326/0003-4819-70-1-155.