Wingerd J, Sponzilli E E
Clin Chem. 1977 Jul;23(7):1310-7.
We measured the concentrations of protein in electrophoretic fractions (albumin and alpha1-, alpha2-, beta, and gamma-globulins) of serum from 9547 white women to determine their relations to age, weight, smoking and other factors. Albumin concentration decreases with age, beta globulin concentration increases. Increasing weight is associated with a decrease in albumin, but with increases in all the globulins. Cigarrete smoking is associated with highly significant differences in all the protein fractions. Surprisingly, very significantly lower concentrations of beta- and gamma-globulins were also found in women who reported a history of tonsillectomy. Height, amenorrhea, education, and alcohol and coffee consumption have some small but statistically significant effects upon the various fractions. Diurnal variation was also slight.
我们测定了9547名白人女性血清电泳组分（白蛋白、α1-、α2-、β和γ球蛋白）中的蛋白质浓度，以确定它们与年龄、体重、吸烟及其他因素的关系。白蛋白浓度随年龄增长而降低，β球蛋白浓度升高。体重增加与白蛋白减少有关，但与所有球蛋白增加有关。吸烟与所有蛋白质组分存在高度显著差异有关。令人惊讶的是，报告有扁桃体切除史的女性中，β和γ球蛋白浓度也非常显著地降低。身高、闭经、教育程度以及酒精和咖啡摄入量对各组分有一些小但具有统计学意义的影响。昼夜变化也很轻微。
