Hieber J P, Dalton D, Shorey J, Combes B
J Pediatr. 1977 Oct;91(4):545-9. doi: 10.1016/s0022-3476(77)80499-x.
The maternal and fetal outcomes of 50 pregnancies complicated by acute viral hepatitis were examined. Twenty (40%) cases were due to type B hepatitis virus. The clinical course of the maternal hepatitis was unaffected by the pregnant state. Maternal hepatitis (type B or nontype B) had no effect on the incidence of congenital malformations, stillbirths, abortions, or intrauterine malnutrition; it did increase the incidence of prematurity (type B 31.6%; nontype B 25%; overall 27.6%) over that seen in the general delivery population (10 to 11%). Eight mothers acquired acute type B hepatitis during the third trimester; two of their infants (25%) were found to be chronic asymptomatic carriers of hepatitis B surface antigen and to have mild, persistent elevations of SGOT for up to 45 months.
对50例合并急性病毒性肝炎的妊娠产妇的母婴结局进行了检查。其中20例（40%）由乙型肝炎病毒引起。产妇肝炎的临床病程不受妊娠状态的影响。产妇肝炎（乙型或非乙型）对先天性畸形、死产、流产或宫内营养不良的发生率没有影响；但与一般分娩人群（10%至11%）相比，确实增加了早产的发生率（乙型为31.6%；非乙型为25%；总体为27.6%）。8名母亲在妊娠晚期患上急性乙型肝炎；她们的两名婴儿（25%）被发现是乙型肝炎表面抗原的慢性无症状携带者，并且血清谷草转氨酶持续轻度升高长达45个月。
