实验性过敏性肺炎：致敏和脱敏小牛血清中的免疫球蛋白G1、G2、M、A和E在微小多孢菌致敏中的情况
Experimental hypersensitivity pneumonitis: serum immunoglobulins G1, G2, M, A and E in Micropolysopra faeni sensitized and desensitized calves.
作者信息
Wilkie B N, Nielsen K H, Little J
出版信息
Int Arch Allergy Appl Immunol. 1978;56(1):79-86. doi: 10.1159/000232006.
PMID:563381
Abstract
Weekly evaluation of serum antibody activity in IgA, IgM, IgG1 and IgG2 as well as serum IgE levels indicates highly significant reduction in IgE and elevation of IgA in calves experimentally desensitized with Micropolyspora faeni soluble antigen. Serum IgG2, IgG1 and IgM levels were also elevated. Results are discussed in the light of the possible significance of reagin-mediated reactions in initiation of hypersensitivity pneumonitis.
摘要
对用嗜热放线菌可溶性抗原进行实验性脱敏的犊牛，每周评估血清中IgA、IgM、IgG1和IgG2抗体活性以及血清IgE水平，结果表明IgE显著降低，IgA升高。血清IgG2、IgG1和IgM水平也升高。根据反应素介导的反应在过敏性肺炎发病中的可能意义对结果进行了讨论。
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