Rosini S, Mazzoncini V
J Hyg Epidemiol Microbiol Immunol. 1977;21(3):309-14.
The anticomplementary properties of two indandione derivatives were studied in vitro on fresh human serum and in vivo on rabbits. In vitro the two substances block immunohemolysis and have direct effect on serum complement activity. One substance blocks the activation of the first complement component and the other the fourth complement component. In vivo, single doses, lower or block complement activity of rabbit serum.
在体外对新鲜人血清以及在体内对兔研究了两种茚二酮衍生物的抗补体特性。在体外，这两种物质可阻断免疫溶血，并对血清补体活性有直接作用。一种物质阻断第一补体成分的激活，另一种阻断第四补体成分的激活。在体内，单剂量较低时可降低或阻断兔血清的补体活性。
