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1
Serum opsonin, bacteria, and polymorphonuclear leukocyte interactions in subacute bacterial endocarditis. Anti-gamma-globulin factors and their interaction with specific opsonins.亚急性细菌性心内膜炎中血清调理素、细菌及多形核白细胞的相互作用。抗γ球蛋白因子及其与特异性调理素的相互作用。
J Clin Invest. 1968 May;47(5):1109-20. doi: 10.1172/JCI105800.
2
The immune response in patients' streptococcal endocarditis.患者链球菌性心内膜炎的免疫反应。
Zentralbl Bakteriol Orig. 1970;214(3):364-76.
3
Phagocytosis in subacute bacterial endocarditis. Localization of the primary opsonic site to Fc fragment.亚急性细菌性心内膜炎中的吞噬作用。主要调理素位点定位于Fc片段。
J Exp Med. 1968 Oct 1;128(4):553-70. doi: 10.1084/jem.128.4.553.
4
Chemical modification of human and rabbit antistaphylococcal gamma G antibodies: effect of acetylation, carbamylation and amidination on opsonic activity.人及兔抗葡萄球菌γG抗体的化学修饰：乙酰化、氨甲酰化和脒化对调理活性的影响。
J Immunol. 1970 Jan;104(1):238-46.
5
Comparative studies of immunoglobulin opsonins in osteomyelitis and other established infections.骨髓炎及其他确诊感染中免疫球蛋白调理素的比较研究。
Immunology. 1969 Aug;17(2):249-65.
6
Opsonic, agglutinating, and complement-fixing antibodies in patients with subacute bacterial endocarditis.亚急性细菌性心内膜炎患者体内的调理素、凝集素及补体结合抗体。
J Lab Clin Med. 1968 Apr;71(4):638-53.
7
Receptors for human gamma G globulin on human neutrophils.人类中性粒细胞上的人γG球蛋白受体
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9
Light chain heterogeneity of 19S and 7S anti-gamma-globulins in rheumatoid arthritis and subacute bacterial endocarditis.类风湿关节炎和亚急性细菌性心内膜炎中19S和7S抗γ球蛋白的轻链异质性
Arthritis Rheum. 1978 May;21(4):438-40. doi: 10.1002/art.1780210406.
10
Opsonization.调理作用
Nouv Rev Fr Hematol. 1974 Mar-Apr;14(2):247-57.

引用本文的文献

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Eur J Pediatr. 1980;133(1):11-6. doi: 10.1007/BF00444748.
3
Effect of rheumatoid factors and normal human sera on immune complex-Fc gamma R interaction.类风湿因子和正常人血清对免疫复合物-FcγR相互作用的影响。
Clin Exp Immunol. 1983 Oct;54(1):225-31.
4
The biological properties of immunoglobulin G and its split products [F(ab')2 and Fab].免疫球蛋白G及其裂解产物[F(ab')2和Fab]的生物学特性。
Klin Wochenschr. 1983 Aug 1;61(15):723-36. doi: 10.1007/BF01497399.
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Experimental endocarditis I. Staphylococcal endocarditis in rabbits resulting from placement of a polyethylene catheter in the right side of the heart.实验性心内膜炎I. 因在兔心脏右侧放置聚乙烯导管而导致的葡萄球菌性心内膜炎。
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Studies of human sera with cytotoxic activity.具有细胞毒性活性的人血清研究。
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J Clin Invest. 1972 Dec;51(12):3007-14. doi: 10.1172/JCI107128.
8
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9
Phagocytosis in subacute bacterial endocarditis. Localization of the primary opsonic site to Fc fragment.亚急性细菌性心内膜炎中的吞噬作用。主要调理素位点定位于Fc片段。
J Exp Med. 1968 Oct 1;128(4):553-70. doi: 10.1084/jem.128.4.553.
10
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本文引用的文献

1
Phagocytosis of particulate complexes of gamma-globulin and rheumatoid factor.γ-球蛋白与类风湿因子颗粒复合物的吞噬作用。
J Immunol. 1962 Apr;88:519-25.
2
ON THE RELATIONSHIPS BETWEEN THE GAMMA-GLOBULIN GENES OF THE GM SYSTEM. A STUDY OF GM GENE PRODUCTS IN SERA, MYELOMA GLOBULINS, AND SPECIFIC ANTIBODIES WITH SPECIAL REFERENCE TO THE GENE GM.关于GM系统γ球蛋白基因之间的关系。血清、骨髓瘤球蛋白和特异性抗体中GM基因产物的研究，特别提及GM基因。
J Exp Med. 1964 Dec 1;120(6):1169-88.
3
STUDIES ON HEAT-LABILE OPSONIN IN RABBIT SERUM.兔血清中热不稳定调理素的研究
J Immunol. 1964 Jan;92:145-54.
4
PROTECTION OF A COMPLEMENT-SENSITIVE ENZYME SYSTEM BY RHEUMATOID FACTOR.类风湿因子对补体敏感酶系统的保护作用。
J Immunol. 1964 Jan;92:139-44.
5
INHIBITION OF COMPLEMENT FIXATION BY HUMAN SERUM. II. THE ACTIVITY OF A GAMMA-LM GLOBULIN AND RHEUMATOID FACTOR IN COMPLEMENT FIXATION REACTIONS.人血清对补体结合的抑制作用。II. γ-LM球蛋白和类风湿因子在补体结合反应中的活性。
J Immunol. 1963 Dec;91:866-72.
6
THE OPSONIC EFFECT OF COMPLEMENT ON THE PHAGOCYTOSIS OF GAMMA-GLOBULIN-COATED BENTONITE PARTICLES.补体对γ-球蛋白包被的膨润土颗粒吞噬作用的调理效应
J Immunol. 1963 Apr;90:607-11.
7
COMPARISON OF THE AGGLUTINABILITY BY RHEUMATOID ARTHRITIC SERA OF SENSITIZED SHEEP CELLS, EXPOSED TO HUMAN C'1, C'4 AND C'2.类风湿性关节炎血清对经人C'1、C'4和C'2作用的致敏绵羊细胞的凝集能力比较
Acta Pathol Microbiol Scand. 1963;59:73-8.
8
Rheumatoid factor, complement, and conglutinin aberrations in patients with subacute bacterial endocarditis.亚急性细菌性心内膜炎患者的类风湿因子、补体及胶固素异常
J Clin Invest. 1962 Mar;41(3):666-75. doi: 10.1172/JCI104523.
9
Effect of mercaptoethanol on complement binding ability of human 7 S gammaglobulin.巯基乙醇对人7S丙种球蛋白补体结合能力的影响。
Proc Soc Exp Biol Med. 1963 Jul;113:609-13. doi: 10.3181/00379727-113-28440.
10
A study of the properties of the Rhesus antibody (Ri) diagnostic for the rheumatoid factor and its application to Gm grouping.一项关于用于类风湿因子诊断的恒河猴抗体（Ri）特性及其在Gm分组中的应用的研究。
Vox Sang. 1962 Sep-Oct;7:591-606. doi: 10.1111/j.1423-0410.1962.tb04289.x.

亚急性细菌性心内膜炎中血清调理素、细菌及多形核白细胞的相互作用。抗γ球蛋白因子及其与特异性调理素的相互作用。

Serum opsonin, bacteria, and polymorphonuclear leukocyte interactions in subacute bacterial endocarditis. Anti-gamma-globulin factors and their interaction with specific opsonins.

作者信息

Messner R P, Laxidal T, Quie P G, Williams R C

出版信息

J Clin Invest. 1968 May;47(5):1109-20. doi: 10.1172/JCI105800.

DOI:10.1172/JCI105800
PMID:5645856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC297263/
Abstract

The effect of anti-gamma-globulin factors on 7S gamma-globulin opsonins from patients with subacute bacterial endocarditis has been examined with a quantitative in vitro phagocytosis system. Human anti-gamma-globulin factors from patients with subacute bacterial endocarditis and rheumatoid arthritis inhibited the opsonic action of 7S gamma-globulin specifically bound to bacteria. A similar antiopsonic effect was obtained with rabbit antiserum to human gammaG globulin. The antiopsonic effect of anti-gamma-globulin factors did not correlate with their ability to potentiate agglutination of bacteria by 7S antibody. Competition was demonstrated between the antiopsonic effect of anti-gamma-globulin factors and the phagocytosis-promoting action of heat-labile serum factors containing hemolytically active complement.

摘要

已使用定量体外吞噬系统研究了抗γ球蛋白因子对亚急性细菌性心内膜炎患者7Sγ球蛋白调理素的作用。来自亚急性细菌性心内膜炎和类风湿性关节炎患者的人抗γ球蛋白因子特异性抑制了与细菌特异性结合的7Sγ球蛋白的调理作用。用兔抗人γG球蛋白抗血清也获得了类似的抗调理作用。抗γ球蛋白因子的抗调理作用与其增强7S抗体对细菌凝集作用的能力无关。已证明抗γ球蛋白因子的抗调理作用与含有溶血活性补体的热不稳定血清因子的促吞噬作用之间存在竞争。