Phair J P, Klippel J, Mackenzie M R
Infect Immun. 1972 Jan;5(1):24-6. doi: 10.1128/iai.5.1.24-26.1972.
Twenty-five patients with endocarditis and serum antiglobulin activity were studied. The antiglobulins were detected by use of the latex agglutination reaction; only eight sera reacted with sensitized sheep cells and one with human O CD erythrocytes coated with anti-CD (Ripley) antibody. Absorption of the sera with the infecting organisms produced a decrease in antiglobulin activity in 10 of these sera. Absorption with other reference bacteria did not lower the titer of latex agglutination in 9 of 10 of these sera. No inhibition of antiglobulin activity by autologous immunoglobulin G was demonstrable. These findings suggest that some antiglobulins interact with the immunoglobulin G-bacterial complex and are analogous to anti-antibodies.
对25例患有心内膜炎且具有血清抗球蛋白活性的患者进行了研究。通过乳胶凝集反应检测抗球蛋白；只有8份血清与致敏绵羊细胞发生反应，1份血清与包被抗CD（里普利）抗体的人O型CD红细胞发生反应。用感染性生物体吸收这些血清后，其中10份血清的抗球蛋白活性降低。用其他参考细菌吸收后，这些血清中有9份的乳胶凝集滴度未降低。未证实自体免疫球蛋白G对抗球蛋白活性有抑制作用。这些发现表明，一些抗球蛋白与免疫球蛋白G-细菌复合物相互作用，类似于抗抗体。
