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[急性虹膜睫状体炎、强直性脊柱炎(别赫捷列夫病)与先天性组织抗原(作者译)]

[Acute iridocyclitis, ankylosing spondylitis (Bechterew) and congenital tissue antigens (author's transl)].

作者信息

Bigar F, Gerber N, von Felten A

出版信息

Klin Monbl Augenheilkd. 1978 Apr;172(4):597-601.

PMID:565849
Abstract

The tiysue antigen HLA-B27 was present in 92.6% of 95 Swiss patients with classical ankylosing spondylitis. This tissue antigen is present in only 7.7% of healthy Swiss blood donors. 36% of all patients had one or several acute attacks of anterior uveitis. This usually follows the onset of joint symptoms. In 4% of the 95 patients the iritis was the first symptom. The combination of acute uveitis and ankylosing spondylitis with the tissue antigen HLA-B27 indicates that not only the spondylitis, but also the uveitis is in many cases genetically determined.

摘要

在95名患有典型强直性脊柱炎的瑞士患者中,组织抗原HLA - B27的阳性率为92.6%。而在健康的瑞士献血者中,该组织抗原的阳性率仅为7.7%。所有患者中有36%曾发生过一次或多次急性前葡萄膜炎发作。这通常在关节症状出现之后。在这95名患者中,有4%的患者虹膜炎是首发症状。急性葡萄膜炎与强直性脊柱炎以及组织抗原HLA - B27同时出现,这表明在许多情况下,不仅脊柱炎,葡萄膜炎也是由基因决定的。

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