Mortimer P E, Stewart J S, Norman A P, Booth C C
Br Med J. 1968 Jul 6;3(5609):7-9. doi: 10.1136/bmj.3.5609.7.
In 9 out of 10 adults in whom a diagnosis of coeliac disease had been made in childhood, the diagnosis was confirmed by the finding of a flat intestinal mucosa. None showed abnormal physical signs, but three had a haemoglobin concentration below 10 g./100 ml. and all those not receiving folic acid supplements showed low serum folate levels. Five had moderate to severe symptoms at the time of investigation, but none was receiving treatment with a gluten-free diet.Periodic investigation of these patients may be necessary throughout life, and if they are found to have malnutrition they should be treated with a gluten-free diet.
在童年时期被诊断为乳糜泻的成年人中,十分之九的人经发现肠道黏膜扁平而确诊。没有人有异常体征,但三人血红蛋白浓度低于10克/100毫升,且所有未补充叶酸的人血清叶酸水平都低。五人在调查时出现中度至重度症状,但无人接受无麸质饮食治疗。可能终生都需要对这些患者进行定期检查,如果发现他们营养不良,就应该用无麸质饮食进行治疗。