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短暂性麸质不耐受

Transient gluten intolerance.

作者信息

Walker-Smith J

出版信息

Arch Dis Child. 1970 Aug;45(242):523-6. doi: 10.1136/adc.45.242.523.

DOI:10.1136/adc.45.242.523
PMID:5506937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1647637/
Abstract

An infant presented with hypoproteinaemic oedema two months after an episode of salmonella enteritis. His oedema subsided spontaneously, but he failed to thrive and small bowel biopsy revealed partial villous atrophy of a severe degree. He was started on a gluten-free diet with a dramatic clinical response and this diet was continued for one year. He was then reinvestigated and small intestinal biopsy was then normal. He was then given a normal diet and a third biopsy performed 16 months later showed that the mucosa was still normal. It is suggested that a transient intolerance to gluten occurred in this patient as a sequel to enteritis, and that a clinical response to a gluten-free diet is not necessarily diagnostic of coeliac disease.

摘要

一名婴儿在沙门氏菌肠炎发作两个月后出现低蛋白血症性水肿。他的水肿自行消退,但生长发育不良,小肠活检显示为重度部分绒毛萎缩。开始给予无麸质饮食,临床反应显著,该饮食持续了一年。之后对他进行复查,小肠活检结果正常。然后给他恢复正常饮食,16个月后进行的第三次活检显示黏膜仍然正常。提示该患者因肠炎继发了对麸质的短暂不耐受,对无麸质饮食的临床反应不一定能诊断为乳糜泻。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/72e2dac920dc/archdisch00884-0101-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/1f6fa40cb352/archdisch00884-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/fff94f80aa97/archdisch00884-0100-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/102acbe4dcbd/archdisch00884-0100-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/cc24592c3704/archdisch00884-0100-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/2d4343b3a957/archdisch00884-0100-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/68b7605d81b9/archdisch00884-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/72e2dac920dc/archdisch00884-0101-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/1f6fa40cb352/archdisch00884-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/fff94f80aa97/archdisch00884-0100-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/102acbe4dcbd/archdisch00884-0100-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/cc24592c3704/archdisch00884-0100-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/2d4343b3a957/archdisch00884-0100-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/68b7605d81b9/archdisch00884-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3acc/1647637/72e2dac920dc/archdisch00884-0101-b.jpg

相似文献

1
Transient gluten intolerance.短暂性麸质不耐受
Arch Dis Child. 1970 Aug;45(242):523-6. doi: 10.1136/adc.45.242.523.
2
[Gluten intolerance in children. Current diagnostic criteria (40 cases followed by biopsy)].[儿童麸质不耐受。当前诊断标准(40例活检随访)]
Ann Med Interne (Paris). 1971 Oct;122(10):911-24.
3
[Gluten enteropathies].[麸质肠病]
Wien Klin Wochenschr. 1967 Aug 4;79(31):605 passim.
4
[The value of biopsy of the small intestine in the diagnosis of primary malabsorption syndrome in childhood].[小肠活检在儿童原发性吸收不良综合征诊断中的价值]
Orv Hetil. 1977 Nov 27;118(48):2891-93.
5
[Gluten intolerance and hypoproteinemia].[麸质不耐受与低蛋白血症]
Minerva Pediatr. 1966 Feb 4;18(3):124-6.
6
Nutritional deficiencies in celiac disease.乳糜泻中的营养缺乏症。
Gastroenterol Clin North Am. 2007 Mar;36(1):93-108, vi. doi: 10.1016/j.gtc.2007.01.006.
7
[Diagnostic value of the histological examination in gluten-sensitive enteropathy].[组织学检查在麸质敏感性肠病中的诊断价值]
Morphol Igazsagugyi Orv Sz. 1981 Apr;21(2):142-9.
8
[Clinical symptoms of gluten-induced enteropathy].[麸质诱导的肠病的临床症状]
Gastroenterologia. 1966;105(5):283-93.
9
Incidence of coeliac disease and transient gluten intolerance in children in a Swedish urban community.瑞典一个城市社区儿童腹腔疾病和短暂性麸质不耐受的发病率。
Acta Paediatr Scand. 1979 May;68(3):397-400. doi: 10.1111/j.1651-2227.1979.tb05026.x.
10
Gluten-free diet: the medical and nutrition management of celiac disease.无麸质饮食:乳糜泻的医学与营养管理
Nutr Clin Pract. 2006 Feb;21(1):1-15. doi: 10.1177/011542650602100101.

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2
Transient non-coeliac gluten sensitivity (NCGS) with markedly reduced villous height/crypt depth ratio.伴有绒毛高度/隐窝深度比值显著降低的短暂性非乳糜泻麸质敏感性(NCGS)。
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Screening for coeliac disease: the meaning of low titers of anti-gliadin antibodies (AGA) in non-coeliac children.

本文引用的文献

1
Plasma proteins and the gastrointestinal tract.血浆蛋白与胃肠道
N Engl J Med. 1962 Mar 29;266:652-60. doi: 10.1056/NEJM196203292661307.
2
GASTROINTESTINAL PROTEIN LEAKAGE IN CELIAC DISEASE AS STUDIED BY LABELED PVP.用标记聚乙烯吡咯烷酮研究乳糜泻患者的胃肠道蛋白质渗漏情况
Am J Dis Child. 1964 Jan;107:58-66. doi: 10.1001/archpedi.1964.02080060060009.
3
Prognosis in early adult life of coeliac children treated with a gluten-free diet.采用无麸质饮食治疗的乳糜泻儿童在成年早期的预后。
乳糜泻筛查:非乳糜泻儿童中抗麦醇溶蛋白抗体(AGA)低滴度的意义。
Eur J Epidemiol. 1997 Jan;13(1):55-9. doi: 10.1023/a:1007301424656.
4
Coeliac disease in Cuban children.古巴儿童的乳糜泻
Arch Dis Child. 1981 Feb;56(2):128-31. doi: 10.1136/adc.56.2.128.
5
Anaphylactic shock in an infant after feeding with a wheat rusk. A transient phenomenon.婴儿喂食小麦面包干后发生过敏性休克。一种短暂现象。
Postgrad Med J. 1981 Dec;57(674):794-5. doi: 10.1136/pgmj.57.674.794.
6
IgA anti-gliadin antibodies in coeliac disease.乳糜泻中的IgA抗麦醇溶蛋白抗体。
Clin Exp Immunol. 1981 Nov;46(2):286-93.
7
New immunofluorescent blood test for gluten sensitivity.用于检测麸质敏感性的新型免疫荧光血液检测
Arch Dis Child. 1981 Nov;56(11):864-8. doi: 10.1136/adc.56.11.864.
8
[Small intestine suction biopsy in childhood: technic complications, importance in diagnosis of intestinal diseases].儿童小肠吸引活检:技术、并发症及在肠道疾病诊断中的重要性
Klin Wochenschr. 1971 Jun 15;49(12):695-705. doi: 10.1007/BF01487104.
9
Coeliac disease. Some still controversial aspects.乳糜泻。一些仍存在争议的方面。
Arch Dis Child. 1972 Apr;47(252):292-8. doi: 10.1136/adc.47.252.292.
10
Plasma food antibodies during withdrawal and reintroduction of dietary gluten in coeliac disease.乳糜泻患者在停用和重新引入膳食麸质期间的血浆食物抗体
Arch Dis Child. 1973 Aug;48(8):583-6. doi: 10.1136/adc.48.8.583.
Br Med J. 1969 May 17;2(5654):401-4. doi: 10.1136/bmj.2.5654.401.
4
Follow-up study of coeliac disease.乳糜泻的随访研究。
Br Med J. 1968 Jul 6;3(5609):7-9. doi: 10.1136/bmj.3.5609.7.
5
Diagnosis of coeliac disease in retrospect.回顾性腹腔疾病诊断
Arch Dis Child. 1968 Jun;43(229):362-4. doi: 10.1136/adc.43.229.362.