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一种光纤反射式血氧计。

A fiberoptic reflection oximeter.

作者信息

Landsman M L, Knop N, Kwant G, Mook G A, Zijlstra W G

出版信息

Pflugers Arch. 1978 Mar 20;373(3):273-82. doi: 10.1007/BF00580835.

Abstract

A catheter tip oximeter is described consisting of a cardiac catheter containing optical fibers, and incandescent light source, a light detection unit and a processing unit. Half of the optical fibers guide the light to the blood at the tip of the catheter, the other half the backscattered (reflected) light to the detection unit. The detection unit contains a dichroic mirror, transmitting most of the light with lambda less than 800 nm and reflecting most of the light with lambda greater than 900 nm, thus splitting the light into two beams. These pass through interference filters with nominal wavelengths of 640 and 920 nm respectively, and are focused on silicium barrier layer photocells. The photocell signals are amplified and fed into a divider giving the ratio of measuring (R640) and compensating (R920) photocell output. The relationship between log R640/R920 and oxygen saturation is represented by a slightly curved line. The relation may be linearized by subtracting a constant voltage from the divided output before taking the logarithm. The slope of the calibration line is dependent on the total haemoglobin concentration. Nonetheless an average calibration line can be used between 70 and 100% oxygen saturation. For 78 measurements of pig blood samples in this range (haemoglobin concentration between 96 and 161 g.1(-1)), the standard deviation of the difference between the fiberoptic oximeter and a Radiometer OSM1 oxygen saturation meter was 1.9% saturation, for 152 samples over the entire saturation range the standard deviation of the difference was 3.1% saturation. The influence of the flow velocity of blood on the light reflection depends on wavelength as well as on oxygen saturation. Therefore, complete compensation for the flow effect is not possible by simple means.

摘要

描述了一种导管顶端血氧计,它由一根包含光纤的心脏导管、一个白炽光源、一个光检测单元和一个处理单元组成。一半光纤将光导向导管顶端的血液,另一半将后向散射(反射)光导向检测单元。检测单元包含一个二向色镜,它透射大部分波长小于800nm的光并反射大部分波长大于900nm的光,从而将光分成两束。这两束光分别通过标称波长为640nm和920nm的干涉滤光片,并聚焦在硅阻挡层光电管上。光电管信号被放大并输入一个除法器,得到测量(R640)和补偿(R920)光电管输出的比值。log R640/R920与氧饱和度之间的关系由一条略呈曲线的线表示。在取对数之前,通过从除法输出中减去一个恒定电压,可以使该关系线性化。校准线的斜率取决于总血红蛋白浓度。尽管如此,在70%至100%的氧饱和度之间仍可使用一条平均校准线。对于该范围内猪血样本的78次测量(血红蛋白浓度在96至161g·1⁻¹之间),光纤血氧计与Radiometer OSM1氧饱和度计之间差异的标准差为1.9%饱和度,对于整个饱和度范围内的152个样本,差异的标准差为3.1%饱和度。血流速度对光反射的影响取决于波长以及氧饱和度。因此,通过简单方法不可能完全补偿血流效应。

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