Sekelj P, Retfalvi S, Lavoie A
Can J Physiol Pharmacol. 1977 Jun;55(3):585-94. doi: 10.1139/y77-081.
Design principles and performance of a new fiberoptic oximeter-densitometer for measurement of blood oxygen saturation are described. This instrument is capable of performing measurements using either an intravascular catheter, flow-through cuvette, or earpiece. The operations of the flow-through cuvette and earpiece are based on the principles of light transmission, that of the catheter on the principles of hemoreflection. The system incorporates five interference filters permitting the selection of a particular wavelength or combination of wavelengths to perform different modes of operation. Estimates using both catheter and cuvette appeared to be independent of variations over a wide range in hematocrit and flow rate. In the range from 20 to 100% saturation the standard deviation of the differences between the in vitro estimates by the catheter and (or) cuvette and the Van Slyke analyses were 1.62 and 1.73%, respectively. In 53 children with congenital heart disease (22 cyanotic) values calculated from readings by the earpiece were related to values of arterial oxygen saturation as measured by American Optical Company reflection oximeter at the time of cardiac catheterization. In the range from 50 to 100% saturation, the regression line between the two techniques was linear and the standard deviation of the differences was 2.89% (3.12% in cyanotic children alone). The method provides a high degree of compensation for variations in skin pigmentation.
本文描述了一种用于测量血氧饱和度的新型光纤血氧计-密度计的设计原理和性能。该仪器能够使用血管内导管、流通比色皿或耳塞进行测量。流通比色皿和耳塞的操作基于光传输原理，导管的操作基于血液反射原理。该系统包含五个干涉滤光片，允许选择特定波长或波长组合以执行不同的操作模式。使用导管和比色皿进行的估计似乎与血细胞比容和流速在很宽范围内的变化无关。在20%至100%饱和度范围内，导管和（或）比色皿的体外估计值与范斯莱克分析之间差异的标准偏差分别为1.62%和1.73%。在53名先天性心脏病患儿（22名青紫型）中，通过耳塞读数计算的值与心脏导管插入术时美国光学公司反射血氧计测量的动脉血氧饱和度值相关。在50%至100%饱和度范围内，两种技术之间的回归线呈线性，差异的标准偏差为2.89%（仅青紫型患儿为3.12%）。该方法对皮肤色素沉着的变化提供了高度补偿。
