通过琼脂平板扩散法对咪唑进行定量分析。
Quantitation of imidazoles by agar-disk diffusion.
作者信息
Grendahl J G, Sung J P
出版信息
Antimicrob Agents Chemother. 1978 Sep;14(3):509-13. doi: 10.1128/AAC.14.3.509.
Abstract
A simple, reliable, and inexpensive assay for quantitation of the imidazole drugs miconazole, RV 40,500, and RV 41,400 was tested. The assay, similar to a Kirby-Bauer test, was sensitive to less than or equal to 0.2 mug of drug per ml and linear from less than or equal to 0.2 to 10.0 mug/ml. Concentration of inoculum and agar depth in test plates was not as critical as the type of medium, amount of inoculum, or type of drug used.
摘要
对一种用于定量测定咪唑类药物咪康唑、RV 40500和RV 41400的简单、可靠且廉价的分析方法进行了测试。该分析方法类似于 Kirby-Bauer 试验，对每毫升小于或等于0.2微克的药物敏感，且在小于或等于0.2至10.0微克/毫升范围内呈线性关系。试验平板中接种物的浓度和琼脂深度不如培养基类型、接种物量或所用药物类型关键。
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2
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3
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