黑色素瘤患者尿液中3-甲氧基酪氨酸的检测
Demonstration of 3-methoxytyrosine in the urine of melanoma patients.
作者信息
Agrup G, Bengtsson M, Falck B, Persson K, Rorsman H, Rosengren A M, Rosengren E
出版信息
Acta Derm Venereol. 1976;56(1):27-31.
PMID:56853
Abstract
With the aid of gas chromatography and mass spectrometry a metabolite of dopa, 3-methoxytyrosine, has been demonstrated in the urine of 2 patients with melanoma metastases, the amounts excreted being 4.0 mg and 8.5 mg/24 hours, respectively. 3-Methoxytyrosine could not with certainty be identified in the urines of two normal subjects.
摘要
借助气相色谱法和质谱分析法，在2例黑素瘤转移患者的尿液中证实了多巴的一种代谢产物3-甲氧基酪氨酸，其排泄量分别为4.0毫克和8.5毫克/24小时。在两名正常受试者的尿液中未能确切鉴定出3-甲氧基酪氨酸。
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