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纳洛酮与鸡体内吗啡及休克增强的强直性静止的相互作用。

Naloxone interactions with morphine-and shock-potentiated tonic immobility in chickens.

作者信息

Peters R H, Hughes R A

出版信息

Pharmacol Biochem Behav. 1978 Aug;9(2):153-6. doi: 10.1016/0091-3057(78)90157-0.

Abstract

Opiate receptor involvement in tonic immobility was examined by administering various does of the opiate antagonist naloxone before measuring morphine-potentiated, shock-poteniated or unpotentiated tonic immobility in chickens. Naloxone attenuated morphine-potentiated, but not shock-potentiated or unpotentiated tonic immobility. Morphine-potentiated tonic immobility appears to be opiate specific.

摘要

通过在测量鸡的吗啡增强、电击增强或未增强的强直性静止之前给予不同剂量的阿片拮抗剂纳洛酮,研究了阿片受体在强直性静止中的作用。纳洛酮减弱了吗啡增强的强直性静止,但对电击增强或未增强的强直性静止没有影响。吗啡增强的强直性静止似乎具有阿片特异性。

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