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长期摄入乙醇对某些小鼠肿瘤生长和扩散的影响。

The effect of chronic ethanol intake on the growth and spread of some murine tumors.

作者信息

Capel I D, Jenner M, Pinnock M H, Dorrell H M, Williams D C

出版信息

Oncology. 1978;35(5):224-6. doi: 10.1159/000225292.

Abstract

The effect of chronic ethanol intake on the growth and spread of some murine tumors has been investigated. The treatment had no effect on the B 16 melanoma but tended to decrease the number of Ehrlich ascites cells. In the case of the Lewis lung carcinoma, administration of ethanol for two weeks tended to lower the number of metastases to the lung without significantly affecting the primary tumor size, whereas more prolonged ethanol intake decreased the weight of the primary tumor in addition to decreasing its dissemination.

摘要

已对长期摄入乙醇对某些小鼠肿瘤生长和扩散的影响进行了研究。该处理对B16黑色素瘤没有影响,但倾向于减少艾氏腹水癌细胞的数量。就Lewis肺癌而言,给予乙醇两周倾向于降低肺转移灶的数量,而对原发肿瘤大小没有显著影响,而更长时间摄入乙醇除了减少其扩散外,还降低了原发肿瘤的重量。

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