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[腹水对艾氏腹水癌和刘易斯肺癌生长的影响]

[The effect of ascitic fluid on the growth of Ehrlich tumor and Lewis carcinoma].

作者信息

Donenko F V, Kabieva A O, Moroz L V

出版信息

Biull Eksp Biol Med. 1992 Jul;114(8):191-3.

PMID:1467491
Abstract

In the study of the effect of ascitic fluid and dialysate of Ehrlich ascites tumor cells (m.m. less than 15 kDa) on the growth of Ehrlich and Lewis carcinoma it was found that the ascitic fluid significantly decreased the size of Ehrlich tumor (by more than 50% on day 9-25 after the tumor cell inoculation). It also reduced Lewis carcinoma tumor volume by more than 30% during 3 weeks after the tumor cells inoculation. Dialysate of Ehrlich tumor cells significantly inhibited the growth of Ehrlich tumor too. It is suggested that this test-system simulates inhibition of a small tumor by a big tumor in vivo.

摘要

在研究艾氏腹水癌细胞(分子量小于15 kDa)的腹水和透析液对艾氏癌和刘易斯癌生长的影响时发现,腹水显著减小了艾氏肿瘤的大小(在接种肿瘤细胞后第9 - 25天减小超过50%)。在接种肿瘤细胞后的3周内,它还使刘易斯癌的肿瘤体积减小了超过30%。艾氏肿瘤细胞的透析液也显著抑制了艾氏肿瘤的生长。有人认为,该测试系统模拟了体内大肿瘤对小肿瘤的抑制作用。

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