Lerke P A, Werner S B, Taylor S L, Guthertz L S
West J Med. 1978 Nov;129(5):381-6.
An outbreak of scombroid poisoning occurred in San Francisco in the fall of 1977. The vehicle was sashimi prepared from spoiled tuna fish. Prompt public health measures prevented further consumption of the implicated food. Laboratory studies showed the presence in the tuna of bacterial species capable of producing large amounts of histamine, a substance strongly implicated in scombroid poisoning. Chemical analysis showed that histamine is very unevenly distributed in the flesh of spoiling tuna, therefore accounting for the sometimes random occurrence of disease among people eating the same food at the same table.
1977年秋季,旧金山爆发了一次组胺中毒事件。中毒媒介是用变质金枪鱼制作的生鱼片。及时采取的公共卫生措施防止了人们进一步食用涉事食品。实验室研究表明,金枪鱼中存在能够产生大量组胺的细菌种类,组胺是一种与组胺中毒密切相关的物质。化学分析表明,组胺在变质金枪鱼的鱼肉中分布极不均匀,因此解释了为何在同一桌食用相同食物的人群中,中毒情况有时会随机发生。