Direction Interarmées du Service de Santé, Forces Françaises du Cap-Vert, Sénégal.
Epidemiol Infect. 2012 Jun;140(6):1008-12. doi: 10.1017/S0950268811001701. Epub 2011 Aug 30.
On 26 November 2010, an outbreak of scombroid fish poisoning occurred in the French Armed Forces in Dakar, Senegal. This chemical intoxication, due to high histamine concentration in fish, is often mistaken for an allergic reaction. A case-control study was undertaken including the 71 cases and 78 randomly selected controls among lunch attendees. The usual symptoms for scombroid fish poisoning were observed in cases, i.e. flushing (85.9%), headache (83.1%), rapid/weak pulse (59.1%) and diarrhoea (47.9%). Symptoms occurred from within a few minutes to up to 3 h following the meal. Most patients quickly recovered with antihistamine and/or symptomatic treatment. Tuna was the only food item positively associated with illness (odds ratio 36.3, 95% confidence interval 6.3-210.0), with the risk of illness increasing with the quantity of fish consumed. No bacterial contamination was found in leftover food, but histamine concentration in tuna was found to be 4900 mg/kg, almost 50-fold higher than the concentration allowed by European regulations. This report is unique because of the large size of the case series - to our knowledge, the largest event of scombroid fish poisoning ever reported - and the chemical and bacteriological analyses results obtained on leftover food.
2010 年 11 月 26 日，塞内加尔达喀尔的法国武装部队发生一起鲭鱼中毒暴发事件。这种化学中毒是由于鱼类中组胺浓度过高引起的，常被误诊为过敏反应。开展了一项病例对照研究，包括午餐参加者中的 71 例病例和 78 名随机选择的对照者。鲭鱼中毒的常见症状在病例中观察到，即潮红（85.9%）、头痛（83.1%）、快速/微弱脉搏（59.1%）和腹泻（47.9%）。症状在餐后数分钟至 3 小时内出现。大多数患者通过抗组胺药和/或对症治疗迅速康复。金枪鱼是唯一与疾病相关的食物（比值比 36.3，95%置信区间 6.3-210.0），随着食用鱼量的增加，患病风险增加。剩余食物中未发现细菌污染，但金枪鱼中的组胺浓度为 4900mg/kg，几乎比欧洲法规允许的浓度高 50 倍。由于该报告具有以下特点而显得独特：病例系列规模大——据我们所知，这是有记录以来最大的一起鲭鱼中毒事件——以及对剩余食物进行的化学和细菌分析结果。
