Stirm S
J Virol. 1968 Oct;2(10):1107-14. doi: 10.1128/JVI.2.10.1107-1114.1968.
A set of five Escherichia coli K phages has been isolated. These phages are adsorbed to and lyse the capsular forms of the host bacteria, whereas their spontaneous, acapsular mutants are not affected. All host strains are heavily encapsulated test strains for E. coli K antigens of the thermostable A type and they readily segregate acapsular mutants. In four of the phage-host systems, all secondary growth obtained was found to be acapsular. When tested for host-range mutants on 38 strains of E. coli and Klebsiella, less than one mutant per 10(5) plaque-forming units was found. No cross-reacting neutralizing antibodies were obtained when rabbits were immunized with the K phages. The latent periods (between 16 and 30 min) and average burst sizes (between 145 and 580) were determined by one-step growth experiments.
已分离出一组五种大肠杆菌K噬菌体。这些噬菌体吸附并裂解宿主细菌的荚膜形式，而它们自发产生的无荚膜突变体则不受影响。所有宿主菌株都是用于热稳定A型大肠杆菌K抗原的高度荚膜化测试菌株，并且它们很容易分离出无荚膜突变体。在四个噬菌体 - 宿主系统中，发现所有二次生长均为无荚膜的。在用K噬菌体免疫兔子时，未获得交叉反应性中和抗体。通过一步生长实验确定了潜伏期（16至30分钟之间）和平均裂解量（145至580之间）。
