正常组织和受辐照组织中组蛋白F1磷酸含量的变化。
Variations in the phosphate content of histone F1 in normal and irradiated tissues.
作者信息
Stevely W S, Stocken L A
出版信息
Biochem J. 1968 Nov;110(2):187-91. doi: 10.1042/bj1100187.
Abstract
- The capacity of the histone-DNA complex to act as a template for RNA synthesis is increased by phosphorylation of histone F1. 2. In regenerating liver, DNA synthesis is preceded by phosphorylation of histone F1. 3. Exposure to ionizing radiation in vivo decreases and delays the phosphorylation of histone F1 in regenerating liver, and decreases it in the hyperplastic kidney. 4. Histone F1 is phosphorylated to a greater extent in dividing than in resting tissues.
摘要
- 组蛋白F1的磷酸化可增强组蛋白-DNA复合物作为RNA合成模板的能力。2. 在再生肝中，DNA合成之前会发生组蛋白F1的磷酸化。3. 体内暴露于电离辐射会降低并延迟再生肝中组蛋白F1的磷酸化，并降低增生肾中组蛋白F1的磷酸化。4. 与静止组织相比，分裂组织中的组蛋白F1磷酸化程度更高。
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本文引用的文献
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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES.从间期淋巴细胞中分离出的抑制性染色质和活性染色质。
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The effect of ionizing radiation on nuclear phosphorylation in the radio-sensitive tissues of the rat.电离辐射对大鼠放射敏感组织中核磷酸化的影响。
Biochem J. 1959 Jul;72(3):519-23. doi: 10.1042/bj0720519.
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Phosphorus assay in column chromatography.柱色谱法中的磷测定
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Isolation of pure and unaltered liver nuclei morphology and biochemical composition.分离出形态和生化组成纯净且未改变的肝细胞核。
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Incorporation of radioactive phosphate into the nucleic acids of brain slices.放射性磷酸盐掺入脑切片的核酸中。
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