Jensen P K, Steven K
Pflugers Arch. 1979 Nov;382(2):179-87. doi: 10.1007/BF00584220.
Tubular compliance is the response of tubular diameter to changes in intratubular pressure [7]. Proximal tubular compliance was determined directly by measurements of tubular diameter and pressure and indirectly using a mathematical model of tubular fluid flow based on measurements of the hydraulic pressure gradients along the tubule under free flow conditions and during an induced pressure reduction at the end of the proximal tubule. The two independent methods yielded similar values for compliance. Proximal tubular compliance was found to depend upon the intratubular pressure: tubular compliance was significantly higher (P less than 0.001) when the intratubular pressure was reduced below normal (1.0 micron cm H2O-1) than when the pressure was increased above the control value (0.4 micron cm H2O-1). Almost identical compliance values were measured in sodium pentobarbital and inactin anaesthetized rats (P greater than 0.8). Intratubularpressure changes resulted in inverse changes in the diameters of the adjacent capillaries, suggesting that the peritubular capillaries are distensible structures.
肾小管顺应性是指肾小管直径对管腔内压力变化的反应[7]。近端肾小管顺应性可通过测量肾小管直径和压力直接测定，也可在自由流动条件下以及近端小管末端诱导减压时，基于沿小管的液压梯度测量值，使用肾小管液流数学模型间接测定。这两种独立方法得出的顺应性值相似。发现近端肾小管顺应性取决于管腔内压力：当管腔内压力降至正常以下（1.0微厘米水柱-1）时，肾小管顺应性显著更高（P小于0.001），而当压力升高至对照值以上（0.4微厘米水柱-1）时则不然。在戊巴比妥钠和安钠咖麻醉的大鼠中测得的顺应性值几乎相同（P大于0.8）。管腔内压力变化导致相邻毛细血管直径呈反向变化，表明管周毛细血管是可扩张结构。
