Mazurek C, Chalvet H, Biozzi G, Stiffel C
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):161-3.
The protective effect produced by pre-treatment with C. parvum is studied in two syngeneic tumours: mammary carcinoma in C3H mice and lymphosarcoma in XVII mice. The best anti-tumour effect is obtained when both C. parvum and tumour cells are injected by the same route, which, however varies for the two tumours. The study of the recovery of C. parvum protective effect after its suppression by a sub-letal dose of x-irradiation shows that, in the C3H mice, it is parallel to the restoration of the antibody response. On the contrary, in XVII mice, the recovery of the protection is obtained in mice still immunologically suppressed.
用微小隐孢子虫进行预处理所产生的保护作用，在两种同基因肿瘤中进行了研究：C3H小鼠的乳腺癌和XVII小鼠的淋巴肉瘤。当微小隐孢子虫和肿瘤细胞通过相同途径注射时，可获得最佳抗肿瘤效果，不过，这两种肿瘤的注射途径有所不同。对微小隐孢子虫保护作用在被亚致死剂量的X射线照射抑制后的恢复情况进行研究表明，在C3H小鼠中，其与抗体反应的恢复情况平行。相反，在XVII小鼠中，在仍处于免疫抑制状态的小鼠中获得了保护作用的恢复。
