口服苯巴比妥对正常蛋白饮食和低蛋白饮食大鼠肝脏微粒体细胞色素P-450及脱甲基活性的影响。 - Suppr

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The effect of oral phenobarbitone on hepatic microsomal cytochrome P-450 and demethylation activity in rats fed normal and low protein diets.

作者信息

Marshall W J, McLean A E

出版信息

Biochem Pharmacol. 1969 Jan;18(1):153-7. doi: 10.1016/0006-2952(69)90020-3.

DOI:10.1016/0006-2952(69)90020-3

PMID:5769345

Abstract

摘要

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The effect of oral phenobarbitone on hepatic microsomal cytochrome P-450 and demethylation activity in rats fed normal and low protein diets.口服苯巴比妥对正常蛋白饮食和低蛋白饮食大鼠肝脏微粒体细胞色素P-450及脱甲基活性的影响。

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Stimulation of hepatic protein synthesis in rats fed an adequate protein diet after a low protein diet.

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Biochem J. 1969 Aug;114(1):7P. doi: 10.1042/bj1140007pa.

Increased renal carcinogenesis by dimethyl nitrosamine in protein deficient rats.蛋白质缺乏的大鼠中，二甲基亚硝胺导致肾癌发生增加。

Br J Exp Pathol. 1970 Dec;51(6):587-90.

The effect of protein deficiency and microsomal enzyme induction by DDT and phenobarbitone on the acute toxicity of chloroform and a pyrrolizidine alkaloid, retrorsine.蛋白质缺乏以及滴滴涕和苯巴比妥对微粒体酶的诱导作用对氯仿和一种吡咯里西啶生物碱——倒千里光碱急性毒性的影响。

Br J Exp Pathol. 1970 Jun;51(3):317-21.

Instant cirrhosis. An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone.速发性肝硬化。一种通过同时给予四氯化碳和苯巴比妥在大鼠中诱导肝硬化的改良方法。

Br J Exp Pathol. 1969 Oct;50(5):502-6.

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The effect of nutrition and hormonal status on cytochrome P-450 and its induction.营养与激素状态对细胞色素P - 450及其诱导作用的影响。

Biochem J. 1969 Dec;115(5):27P-28P. doi: 10.1042/bj1150027p.

A dietary factor required for the induction of hepatic microsomal cytochrome P-450 by phenobarbitone.苯巴比妥诱导肝微粒体细胞色素P - 450所需的膳食因素。

Biochem J. 1969 Oct;114(4):77P-78P. doi: 10.1042/bj1140077pb.

The effect of linoleic acid, peroxidation and antioxidants on induction of cytochrome P-450 in rat liver.亚油酸、过氧化作用及抗氧化剂对大鼠肝脏细胞色素P - 450诱导的影响。

Biochem J. 1971 Jul;123(4):28P. doi: 10.1042/bj1230028pa.

A requirement for dietary lipids for induction of cytochrome P-450 by phenobarbitone in rat liver microsomal fraction.大鼠肝微粒体部分中苯巴比妥诱导细胞色素P-450所需的膳食脂质。

Biochem J. 1971 May;122(4):569-73. doi: 10.1042/bj1220569.

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