• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

乙醇诱导猪和兔血液中微聚集体的形成。一项体外研究。

Ethanol-induced microaggregate formation in pig and rabbit blood. An in vitro study.

作者信息

Elmér O, Göransson G, Saku M, Bengmark S

出版信息

Thromb Haemost. 1977 Apr 30;37(2):344-50.

PMID:577632
Abstract

Increased microaggregate formation was found after mixing ethanol with blood from pig and rabbit in vitro, measured with Swank's Screen Filtration pressure method. Final ethanol concentrations were in the range found in ethanol-intoxication in man. No rise in SFP was noticed when plasma with 10,000 platelets/microliter was used. It is therefore doubtful that altered plasma proteins caused the rise in SFP. It is suggested that if a direct effect of ethanol upon platelet aggregation exists in vivo, it may be of importance in acute ethanol intoxication and in chronic alcoholism.

摘要

体外将乙醇与猪和兔的血液混合后,采用斯旺克滤网过滤压力法测量发现微聚集体形成增加。最终乙醇浓度处于人体乙醇中毒时的浓度范围内。当使用每微升含10000个血小板的血浆时,未观察到滤网过滤压力(SFP)升高。因此,血浆蛋白改变导致SFP升高这一点值得怀疑。有人提出,如果乙醇在体内对血小板聚集有直接作用,那么它可能在急性乙醇中毒和慢性酒精中毒中起重要作用。

相似文献

1
Ethanol-induced microaggregate formation in pig and rabbit blood. An in vitro study.乙醇诱导猪和兔血液中微聚集体的形成。一项体外研究。
Thromb Haemost. 1977 Apr 30;37(2):344-50.
2
Circulating microaggregates after gastric administration of ethanol in the pig.猪胃内给予乙醇后循环中的微聚集体。
Eur Surg Res. 1980;12(5):333-42. doi: 10.1159/000128139.
3
In vitro effect of ethanol on ADP and collagen-induced platelet aggregation.乙醇对二磷酸腺苷(ADP)和胶原诱导的血小板聚集的体外作用。
Thromb Haemost. 1981 Dec 23;46(4):673-5.
4
Increased bleeding during liver resection in ethanol-intoxicated rats.乙醇中毒大鼠肝切除术中出血增加。
Thromb Haemost. 1980 Jul 15;43(3):203-7.
5
Sensitivity of thrombin-induced platelet aggregation to inhibition by ethanol.凝血酶诱导的血小板聚集对乙醇抑制作用的敏感性。
Clin Chim Acta. 2009 Apr;402(1-2):156-9. doi: 10.1016/j.cca.2008.12.036. Epub 2009 Jan 9.
6
Acute administration of ethanol to rabbits inhibits thrombus formation induced by indwelling aortic catheters.
Lab Invest. 1990 Dec;63(6):742-5.
7
Effects of ethanol on pathways of platelet aggregation in vitro.乙醇对体外血小板聚集途径的影响。
Thromb Haemost. 1988 Jun 16;59(3):383-7.
8
[The acute and chronic action of ethanol on blood serum proteins in rats].[乙醇对大鼠血清蛋白的急性和慢性作用]
Farmakol Toksikol. 1990 Nov-Dec;53(6):56.
9
Platelet function during acetaldehyde intoxication in healthy male volunteers.健康男性志愿者乙醛中毒期间的血小板功能
Alcohol Alcohol Suppl. 1987;1:587-90.
10
Effects of acute, moderate ethanol consumption on human platelet aggregation in platelet-rich plasma and whole blood.急性、适度饮酒对富血小板血浆和全血中人类血小板聚集的影响。
Alcohol Clin Exp Res. 2000 Apr;24(4):528-34.

引用本文的文献

1
Estimation of anti-platelet drugs on human platelet aggregation with a novel whole blood aggregometer by a screen filtration pressure method.通过筛滤压力法,使用新型全血凝集仪评估抗血小板药物对人血小板聚集的影响。
Br J Pharmacol. 2001 Aug;133(8):1396-404. doi: 10.1038/sj.bjp.0704204.