Field E J, Cook D B
Br Med J. 1969 Apr 26;2(5651):227-9. doi: 10.1136/bmj.2.5651.227.
Antilymphocyte serum prepared in the rabbit against guinea-pig lymph node cells produces a sustained weight loss when injected into normal guinea-pigs over 14 days, compared with a very transient loss produced by normal rabbit serum. Antilymphocyte serum also produces a much greater increase in plasma cortisol level than normal rabbit serum. Part of this effect may be due to adrenal stimulation, and further studies of its activity in adrenalectomized animals are suggested.
用兔制备的抗豚鼠淋巴结细胞抗淋巴细胞血清，给正常豚鼠注射14天，会导致体重持续减轻，而正常兔血清注射后只会引起非常短暂的体重下降。抗淋巴细胞血清还会使血浆皮质醇水平的升高幅度远大于正常兔血清。这种效应部分可能归因于肾上腺刺激，因此建议进一步研究其在肾上腺切除动物中的活性。
