Müller-Tyl E, Salzer H, Altmann P, Müller M M
Z Geburtshilfe Perinatol. 1977 Aug;181(4):251-9.
12 pregnant females in the last trimester were subjected to serial amniocentesis. Although there was medical indication for amniocentesis the pregnancies were normal. All samples were evaluated with four different methods. We used two physical (Wilhelmy balance and foam test) and two chemical (L/S ratio densitometrically and planimetrically measured) methods. The Curves of individual pregnancies were compared with the reference values of 109 samples of amniotic liquid of uncomplicated pregnancies. Reference values for the various techniques reported in the literature are generally based on aggregate data collected from a number of pregnant females, which are then consolidated to obtain mean values for each gestational week. We found a continuous rise of all parameters, both in the reference value and in eight individual pregnancies. Besides we found a strikingly extraordinary run of the curves in four individual pregnancies. Here we recognized a rapid ascent and descent of surfactant concentration within short periods, which were not identical with the reference values. All four methods showed results with a statistical significant conformity, only the foam test showed a little lower significance.
12名处于妊娠晚期的孕妇接受了系列羊膜腔穿刺术。尽管进行羊膜腔穿刺术有医学指征，但这些妊娠均属正常。所有样本均采用四种不同方法进行评估。我们使用了两种物理方法（威廉米天平法和泡沫试验）和两种化学方法（通过密度测定法和面积测量法测量卵磷脂/鞘磷脂比值）。将个体妊娠的曲线与109份正常妊娠羊水样本的参考值进行比较。文献中报道的各种技术的参考值通常基于从许多孕妇收集的汇总数据，然后将这些数据合并以获得每个孕周的平均值。我们发现参考值和8例个体妊娠中所有参数均持续上升。此外，我们发现4例个体妊娠的曲线走势异常显著。在此我们观察到表面活性剂浓度在短时间内迅速上升和下降，这与参考值不同。所有四种方法的结果均具有统计学上的显著一致性，只有泡沫试验的显著性略低。
