Kinoshita K
Nihon Sanka Fujinka Gakkai Zasshi. 1982 Jun;34(6):685-92.
Ninety seven amniotic fluid samples from 89 pregnant women ranging from 9 to 41 weeks of gestation were analyzed for fetal lung maturity by the fluorescence polarization (FP) method and the values were compared with three other methods; lecithin/sphingomyelin (L/S) ratio, shake test and optical density at 650 nm. Of 89 cases 14 were complicated pregnancies. Three respiratory distress syndrome (RDS) was predicted by FP method. FLuorescence polarization (FP) values of amniotic fluid samples declined abruptly from about 34 weeks of gestation in normal pregnancy. The data suggest that the lung maturity threshold of FP value is 0.333. The false negative and false positive results for the FP value were 1.4% and 0%, respectively. There was a significant correlation between FP value and L/S ration (r = 0.766). Among the four methods tested the FP method is more advantageous than the others in reliability, accuracy, reproducibility, operational simplicity and rapidity.
对89名孕周在9至41周的孕妇的97份羊水样本采用荧光偏振（FP）法分析胎儿肺成熟度，并将这些值与其他三种方法进行比较，即卵磷脂/鞘磷脂（L/S）比值、振荡试验和650nm处的光密度。89例中有14例为复杂妊娠。FP法预测出3例呼吸窘迫综合征（RDS）。正常妊娠时，羊水样本的荧光偏振（FP）值从约34孕周开始急剧下降。数据表明，FP值的肺成熟阈值为0.333。FP值的假阴性和假阳性结果分别为1.4%和0%。FP值与L/S比值之间存在显著相关性（r = 0.766）。在所测试的四种方法中，FP法在可靠性、准确性、可重复性、操作简便性和快速性方面比其他方法更具优势。
