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医用123I的放射化学纯度(作者译)

[Radiochemical purity of 123I for medical use (author's transl)].

作者信息

Abural T, Homma Y, Murakami Y

出版信息

Radioisotopes. 1977 Mar;26(3):146-50. doi: 10.3769/radioisotopes.26.3_146.

DOI:10.3769/radioisotopes.26.3_146
PMID:578930
Abstract

123I for use in clinical diagnostic procedures has been produced by bombarding antimony with 40 MeV 3He particles. The purity of 123I was measured with a Ge(Li)spectrometer and a low energy Ge(Li) detector. The 123I-product was followed for 1.5 months with a well-type NaI scintillation counter to establish the half-life and confirm the identity of the nuclides. In order to minimize the yield of 121I the optimum cooling time and chemical procedures are presented. After 20 h cooling, the 121I, 124I and 125I contaminants were about 1.8, 4.3 and 0.04% respectively. These values were in agreement with those calculated from the thick-target yield curves. The calculated absorbed dose to the thyroid by the 123I and by-product nuclides were only 4.3 and 7.3% of 131I. 123I could be measured at the window of 99mTc of a NaI scintillation camera and a curie-meter with an error of 10%.

摘要

用于临床诊断程序的123I是通过用40兆电子伏特的3He粒子轰击锑而产生的。用锗(锂)谱仪和低能锗(锂)探测器测量123I的纯度。用井型碘化钠闪烁计数器对123I产物跟踪1.5个月,以确定半衰期并确认核素的身份。为了使121I的产率最小化,给出了最佳冷却时间和化学程序。冷却20小时后,121I、124I和125I污染物分别约为1.8%、4.3%和0.04%。这些值与根据厚靶产率曲线计算的值一致。123I和副产物核素对甲状腺的计算吸收剂量仅为131I的4.3%和7.3%。123I可以在碘化钠闪烁相机的99mTc窗口和居里计上进行测量,误差为10%。

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