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卵磷脂 - 水体系中相平衡的氘核磁共振研究。

Deuteron nuclear magnetic resonance studies of phase equilibria in a lecithin-water system.

作者信息

Ulmius J, Wennerström H, Lindblom G, Arvidson G

出版信息

Biochemistry. 1977 Dec 27;16(26):5742-5. doi: 10.1021/bi00645a014.

DOI:10.1021/bi00645a014
PMID:579320
Abstract

Water deuteron NMR spectra have been studied for the system dipalmitoyllecithin (DPL)-heavy water (D2O) at different compositions and temperatures. From an analysis of the spectra in terms of quadrupole splittings, a phase diagram has been constructed for the temperature range 25-60 degrees C and the composition range 4-15 mol of D2O/mol of DPL. Evidence is given that the "pretransition" observed by differential scanning calorimetry is caused by a crossing of a three-phase line. Strong support for a specific hydration of about 11 water molecules per lecithin molecule in the phase between the pretransition and main transition is also found.

摘要

已对不同组成和温度下的二棕榈酰卵磷脂（DPL）-重水（D2O）体系的水氘核磁共振谱进行了研究。根据四极分裂对光谱进行分析，构建了25-60摄氏度温度范围和4-15摩尔D2O/摩尔DPL组成范围内的相图。有证据表明，差示扫描量热法观察到的“预转变”是由三相线的交叉引起的。还发现了有力证据，支持在预转变和主转变之间的相中每个卵磷脂分子约有11个水分子的特定水合作用。

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