某些抗血吸虫药的代谢效应。关于“Bilharcid”对正常大鼠肝脏琥珀酸氧化抑制作用的研究。
Metabolic effects of some antibilharzial drugs. Studies on the inhibitory action of "bilharcid" on succinate oxidation in normal rat liver.
作者信息
Sharaf A A, el-Sherbini A, Abdulla W A
出版信息
Egypt J Bilharz. 1978;4(1):35-45.
PMID:580604
Abstract
THE INHIBITION of succinate oxidation by Piperazine diantimonyl tartarate (Bilharcid) could be in part attributed to accumulation of oxaloacetate. This is discussed with reference to the effect of ATP, glutamate and cysteine on the reversal of the inhibitory action, of the drug on succinate oxidation.
摘要
酒石酸氧锑哌嗪（Bilharcid）对琥珀酸氧化的抑制作用部分可归因于草酰乙酸的积累。本文结合三磷酸腺苷（ATP）、谷氨酸和半胱氨酸对该药物抑制琥珀酸氧化作用的逆转效应进行了讨论。
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